Migration of highly-skilled workforce from Russia (including Russian university graduates) continues to grow, threatening the possibility of sustainable development of the country due to the loss of human capital. The article discusses migration intention determinants of talented graduates and explores the role of talent management practices in overcoming brain drain in the Russian context. Using logistic regression model we examine the relationship between graduates’ migration intentions and individual, industry and country-level factors. We also discuss the potential role of business in solving the problem of human capital outflow, namely through the implementation of talent management practices acting as mechanisms for retention of talented graduates of leading Russian universities in the country.