(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties

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(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties. / Paramonova, Polina ; Sharonova, Tatiana ; Kalinin, Stanislav ; Chupakhin, Evgeny; Bunev, Alexander; Krasavin, Mikhail.

In: Mendeleev Communications , Vol. 32, No. 2, 01.03.2022, p. 176-177.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{a94cb27befea4ef089c90c916b68184f,

title = "(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties",

abstract = "The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic {\textquoteleft}Michael acceptor{\textquoteright} motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.",

keywords = "Anti-proliferative agents, Cell viability, Diazo coupling, Enzyme inhibitors, Michael acceptors, MTT assay, Rhodium catalysis, Sulfonamides",

author = "Polina Paramonova and Tatiana Sharonova and Stanislav Kalinin and Evgeny Chupakhin and Alexander Bunev and Mikhail Krasavin",

note = "Publisher Copyright: {\textcopyright} 2022",

year = "2022",

month = mar,

day = "1",

doi = "10.1016/j.mencom.2022.03.007",

language = "English",

volume = "32",

pages = "176--177",

journal = "Mendeleev Communications",

issn = "0959-9436",

publisher = "Elsevier",

number = "2",

}

RIS

TY - JOUR

T1 - (E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties

AU - Paramonova, Polina

AU - Sharonova, Tatiana

AU - Kalinin, Stanislav

AU - Chupakhin, Evgeny

AU - Bunev, Alexander

AU - Krasavin, Mikhail

PY - 2022/3/1

Y1 - 2022/3/1

N2 - The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.

AB - The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.

KW - Anti-proliferative agents

KW - Cell viability

KW - Diazo coupling

KW - Enzyme inhibitors

KW - Michael acceptors

KW - MTT assay

KW - Rhodium catalysis

KW - Sulfonamides

UR - http://www.scopus.com/inward/record.url?scp=85127343163&partnerID=8YFLogxK

U2 - 10.1016/j.mencom.2022.03.007

DO - 10.1016/j.mencom.2022.03.007

M3 - Article

AN - SCOPUS:85127343163

VL - 32

SP - 176

EP - 177

JO - Mendeleev Communications

JF - Mendeleev Communications

SN - 0959-9436

IS - 2

ER -

ID: 94226808