Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
(E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties. / Paramonova, Polina; Sharonova, Tatiana; Kalinin, Stanislav; Chupakhin, Evgeny; Bunev, Alexander; Krasavin, Mikhail.
в: Mendeleev Communications , Том 32, № 2, 01.03.2022, стр. 176-177.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - (E)-3-Arylidene-4-diazopyrrolidine-2,5-diones conveniently elaborated into cytotoxic compounds bearing primary sulfonamide and Michael acceptor moieties
AU - Paramonova, Polina
AU - Sharonova, Tatiana
AU - Kalinin, Stanislav
AU - Chupakhin, Evgeny
AU - Bunev, Alexander
AU - Krasavin, Mikhail
N1 - Publisher Copyright: © 2022
PY - 2022/3/1
Y1 - 2022/3/1
N2 - The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.
AB - The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.
KW - Anti-proliferative agents
KW - Cell viability
KW - Diazo coupling
KW - Enzyme inhibitors
KW - Michael acceptors
KW - MTT assay
KW - Rhodium catalysis
KW - Sulfonamides
UR - http://www.scopus.com/inward/record.url?scp=85127343163&partnerID=8YFLogxK
U2 - 10.1016/j.mencom.2022.03.007
DO - 10.1016/j.mencom.2022.03.007
M3 - Article
AN - SCOPUS:85127343163
VL - 32
SP - 176
EP - 177
JO - Mendeleev Communications
JF - Mendeleev Communications
SN - 0959-9436
IS - 2
ER -
ID: 94226808