The earlier described (E)-3-arylidene-4-diazopyrrolidine-2,5-diones have been elaborated into two distinct series of compounds both bearing a primary sulfonamide moiety and an electrophilic ‘Michael acceptor’ motif. These compounds demonstrated cytotoxicity against colorectal cancer cell line HCT 116.

Original languageEnglish
Pages (from-to)176-177
Number of pages2
JournalMendeleev Communications
Volume32
Issue number2
DOIs
StatePublished - 1 Mar 2022

    Research areas

  • Anti-proliferative agents, Cell viability, Diazo coupling, Enzyme inhibitors, Michael acceptors, MTT assay, Rhodium catalysis, Sulfonamides

    Scopus subject areas

  • Chemistry(all)

ID: 94226808