Two novel polytellurite-chlorides Pb₅Cu₂(Te₄O₁₁)Cl₈ (1) and CdCu₂(Te₃O₈)Cl₂ (2) were obtained by a chemical vapor transport (CVT-reactions) reactions. The structure of 1 is based on [Pb₅Cu₂(Te₄O₁₁)]^8 + one-dimensional blocks with full and partially occupied Cl sites around. The structure of 2 can be described as being formed by two types of one-dimensional units formed by Cd,Cu-centered polyhedra and TeO₃, TeO₄ pyramids sharing via common O atoms into electroneutral [CdCu₂(Te₃O₈)Cl₂]⁰ sheets. Obtaining of novel polytellurite-chlorides demonstrates effectiveness of CVT techniques for preparation of different tellurite-based complex layered materials.