Research output: Contribution to journal › Article › peer-review
It is known that heterologous protein production in microorganisms has negative influence upon a host cell. In this regard, of particular interest is to know the fate of recombinant proteins in a cell. In this study, it was shown that NLS of bovine gamma-interferon functions in yeast Pichia pastoris cells. The absence of the C-terminal NLS of bovine gamma-interferon leads to cytoplasmic localization of the recombinant protein.
| Translated title of the contribution | Nuclear localization sequence of bovine gamma-interferon provides translocation of recombinant protein to yeast Pichia pastoris cell nucleus |
|---|---|
| Original language | Russian |
| Pages (from-to) | 863-868 |
| Number of pages | 6 |
| Journal | Цитология |
| Volume | 52 |
| Issue number | 10 |
| State | Published - 2010 |
ID: 5120583