Effect of taurine o binding of 45Ca2+ and 8-aniline-I-naphthaline culfonate by microsomes of rat brain cells was studied. Increased accumulation of Ca2+ in phospholipids of microsomes as well as a distinct decrease in the number of sites for binding of 8-aniline-I-naphthaline sulfonate were observed in presence of taurine. Activity of Ca2+-ATPase was simultaneously increased. The data obtained suggest that the effect of taurine on biomembranes is related to local alterations in their surface charge.

Переведенное названиеEffect of taurine on 45Ca2+ binding by the microsomal membranes of brain cells
Язык оригиналарусский
Страницы (с-по)565-8
Число страниц4
ЖурналVoprosy Meditsinskoi Khimii
Том25
Номер выпуска5
СостояниеОпубликовано - 1 сен 1979

    Области исследований

  • Anilino Naphthalenesulfonates/metabolism, Animals, Brain/metabolism, Calcium/metabolism, Calcium Radioisotopes, Cations, Divalent, Cell Membrane/drug effects, Endoplasmic Reticulum/metabolism, Microsomes/drug effects, Protein Binding/drug effects, Rats, Taurine/pharmacology

ID: 38737819