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Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives. / Osinnikova, D. N.; Moroshkina, E. B.; Glushkina, D. M.

в: Journal of Physics: Conference Series, Том 661, № 1, 012020, 02.12.2015.

Результаты исследований: Научные публикации в периодических изданиях › статья в журнале по материалам конференции › Рецензирование

Harvard

Osinnikova, DN, Moroshkina, EB & Glushkina, DM 2015, 'Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives', Journal of Physics: Conference Series, Том. 661, № 1, 012020. https://doi.org/10.1088/1742-6596/661/1/012020

APA

Osinnikova, D. N., Moroshkina, E. B., & Glushkina, D. M. (2015). Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives. Journal of Physics: Conference Series, 661(1), [012020]. https://doi.org/10.1088/1742-6596/661/1/012020

Vancouver

Osinnikova DN, Moroshkina EB, Glushkina DM. Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives. Journal of Physics: Conference Series. 2015 Дек. 2;661(1). 012020. https://doi.org/10.1088/1742-6596/661/1/012020

Author

Osinnikova, D. N. ; Moroshkina, E. B. ; Glushkina, D. M. / Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives. в: Journal of Physics: Conference Series. 2015 ; Том 661, № 1.

BibTeX

@article{bfba0ad74cab4e2993171b1613a2ca67,
title = "Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives",
abstract = "Interaction of native calf thymus DNA (ctDNA) with phenacylimidazo[5,1- a]isoquinoline derivatives was studied by the methods of spectrophotometry, viscometry, isothermal titration calorimetry (ITC) and dynamic birefringence. It was found that both of investigated compounds form complexes with the DNA molecule, the structure of compounds affects the mode of binding these ligands to DNA. The primary binding mode can not be described by the classical models of groove binding or intercalation. It has been suggested that the primary mode of binding is partial intercalation.",
author = "Osinnikova, {D. N.} and Moroshkina, {E. B.} and Glushkina, {D. M.}",
note = "Publisher Copyright: {\textcopyright} Published under licence by IOP Publishing Ltd.; 17th Russian Youth Conference on Physics and Astronomy, PhysicA.SPb 2014 ; Conference date: 28-10-2014 Through 30-10-2014",
year = "2015",
month = dec,
day = "2",
doi = "10.1088/1742-6596/661/1/012020",
language = "English",
volume = "661",
journal = "Journal of Physics: Conference Series",
issn = "1742-6588",
publisher = "IOP Publishing Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - Thermodynamics of interaction and structure of DNA complexes with phenacylimidazo[5,1-a]isoquinoline derivatives

AU - Osinnikova, D. N.

AU - Moroshkina, E. B.

AU - Glushkina, D. M.

N1 - Publisher Copyright: © Published under licence by IOP Publishing Ltd.

PY - 2015/12/2

Y1 - 2015/12/2

N2 - Interaction of native calf thymus DNA (ctDNA) with phenacylimidazo[5,1- a]isoquinoline derivatives was studied by the methods of spectrophotometry, viscometry, isothermal titration calorimetry (ITC) and dynamic birefringence. It was found that both of investigated compounds form complexes with the DNA molecule, the structure of compounds affects the mode of binding these ligands to DNA. The primary binding mode can not be described by the classical models of groove binding or intercalation. It has been suggested that the primary mode of binding is partial intercalation.

AB - Interaction of native calf thymus DNA (ctDNA) with phenacylimidazo[5,1- a]isoquinoline derivatives was studied by the methods of spectrophotometry, viscometry, isothermal titration calorimetry (ITC) and dynamic birefringence. It was found that both of investigated compounds form complexes with the DNA molecule, the structure of compounds affects the mode of binding these ligands to DNA. The primary binding mode can not be described by the classical models of groove binding or intercalation. It has been suggested that the primary mode of binding is partial intercalation.

UR - http://www.scopus.com/inward/record.url?scp=84956856344&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/661/1/012020

DO - 10.1088/1742-6596/661/1/012020

M3 - Conference article

AN - SCOPUS:84956856344

VL - 661

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

SN - 1742-6588

IS - 1

M1 - 012020

T2 - 17th Russian Youth Conference on Physics and Astronomy, PhysicA.SPb 2014

Y2 - 28 October 2014 through 30 October 2014

ER -

ID: 100855380