Standard

The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures. / Chernigovskaya, E.V.; Korotkov, A.A.; Nikitina, L.S.; Dorofeeva, N.A.; Glazova, M.V.

в: Neurological Research, Том 37, № 12, 2015, стр. 1108-1117.

Результаты исследований: Научные публикации в периодических изданиях › статья

Harvard

Chernigovskaya, EV, Korotkov, AA, Nikitina, LS, Dorofeeva, NA & Glazova, MV 2015, 'The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures', Neurological Research, Том. 37, № 12, стр. 1108-1117. https://doi.org/10.1080/01616412.2015.1114288

APA

Chernigovskaya, E. V., Korotkov, A. A., Nikitina, L. S., Dorofeeva, N. A., & Glazova, M. V. (2015). The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures. Neurological Research, 37(12), 1108-1117. https://doi.org/10.1080/01616412.2015.1114288

Vancouver

Chernigovskaya EV, Korotkov AA, Nikitina LS, Dorofeeva NA, Glazova MV. The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures. Neurological Research. 2015;37(12):1108-1117. https://doi.org/10.1080/01616412.2015.1114288

Author

Chernigovskaya, E.V. ; Korotkov, A.A. ; Nikitina, L.S. ; Dorofeeva, N.A. ; Glazova, M.V. / The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures. в: Neurological Research. 2015 ; Том 37, № 12. стр. 1108-1117.

BibTeX

@article{ac40437eb3434bbca8bf9458273e46e1,
title = "The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures",
abstract = "{\textcopyright} 2016 Taylor & Francis. It is known that perirhinal/insular cortices participate in the transmission of sensory stimuli to the motor cortex,thus coordinating motor activity during seizures. In the present study we analysed seizure-related proteins, suchas GABA, glutamate, ERK1/2 and the synaptic proteins in the insular cortex of Krushinsky-Molodkina (KM) ratsgenetically prone to audiogenic seizures (AGS). We compared seizure-na{\"i}ve and seizure-experienced KM ratswith control Wistar rats in order to distinguish whether seizure-related protein changes are associated with seizureevent or representing an inhered pathological abnormality that determines predisposition to AGS. Our datademonstrated an increased level of vesicular glutamate transporter VGLUT2 in na{\"i}ve and seizure-experienced KMrats, while glutamic acid decarboxylases GAD65 and GAD67 levels were unchanged. Evaluation of the synaptic proteins showed a decrease in SNAP-25 and upregulation of synapsin I phosphorylation in both groups of KM ratsin compari",
author = "E.V. Chernigovskaya and A.A. Korotkov and L.S. Nikitina and N.A. Dorofeeva and M.V. Glazova",
year = "2015",
doi = "10.1080/01616412.2015.1114288",
language = "English",
volume = "37",
pages = "1108--1117",
journal = "Neurological Research",
issn = "0161-6412",
publisher = "Maney Publishing",
number = "12",

}

RIS

TY - JOUR

T1 - The expression and distribution of seizure-related and synaptic proteins in the insular cortex of rats genetically prone to audiogenic seizures

AU - Chernigovskaya, E.V.

AU - Korotkov, A.A.

AU - Nikitina, L.S.

AU - Dorofeeva, N.A.

AU - Glazova, M.V.

PY - 2015

Y1 - 2015

N2 - © 2016 Taylor & Francis. It is known that perirhinal/insular cortices participate in the transmission of sensory stimuli to the motor cortex,thus coordinating motor activity during seizures. In the present study we analysed seizure-related proteins, suchas GABA, glutamate, ERK1/2 and the synaptic proteins in the insular cortex of Krushinsky-Molodkina (KM) ratsgenetically prone to audiogenic seizures (AGS). We compared seizure-naïve and seizure-experienced KM ratswith control Wistar rats in order to distinguish whether seizure-related protein changes are associated with seizureevent or representing an inhered pathological abnormality that determines predisposition to AGS. Our datademonstrated an increased level of vesicular glutamate transporter VGLUT2 in naïve and seizure-experienced KMrats, while glutamic acid decarboxylases GAD65 and GAD67 levels were unchanged. Evaluation of the synaptic proteins showed a decrease in SNAP-25 and upregulation of synapsin I phosphorylation in both groups of KM ratsin compari

AB - © 2016 Taylor & Francis. It is known that perirhinal/insular cortices participate in the transmission of sensory stimuli to the motor cortex,thus coordinating motor activity during seizures. In the present study we analysed seizure-related proteins, suchas GABA, glutamate, ERK1/2 and the synaptic proteins in the insular cortex of Krushinsky-Molodkina (KM) ratsgenetically prone to audiogenic seizures (AGS). We compared seizure-naïve and seizure-experienced KM ratswith control Wistar rats in order to distinguish whether seizure-related protein changes are associated with seizureevent or representing an inhered pathological abnormality that determines predisposition to AGS. Our datademonstrated an increased level of vesicular glutamate transporter VGLUT2 in naïve and seizure-experienced KMrats, while glutamic acid decarboxylases GAD65 and GAD67 levels were unchanged. Evaluation of the synaptic proteins showed a decrease in SNAP-25 and upregulation of synapsin I phosphorylation in both groups of KM ratsin compari

U2 - 10.1080/01616412.2015.1114288

DO - 10.1080/01616412.2015.1114288

M3 - Article

VL - 37

SP - 1108

EP - 1117

JO - Neurological Research

JF - Neurological Research

SN - 0161-6412

IS - 12

ER -

ID: 3988426