Standard

The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception. / Apryatin, S. A.; Shipelin, V. A.; Trusov, N. V.; Mzhel’skaya, K. V.; Kirbaeva, N. V.; Soto, J. S.; Riger, N. A.; Gmoshinski, I. V.

в: Biology Bulletin, Том 47, № 4, 01.07.2020, стр. 407-416.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Apryatin, SA, Shipelin, VA, Trusov, NV, Mzhel’skaya, KV, Kirbaeva, NV, Soto, JS, Riger, NA & Gmoshinski, IV 2020, 'The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception', Biology Bulletin, Том. 47, № 4, стр. 407-416. https://doi.org/10.1134/S1062359020040020

APA

Apryatin, S. A., Shipelin, V. A., Trusov, N. V., Mzhel’skaya, K. V., Kirbaeva, N. V., Soto, J. S., Riger, N. A., & Gmoshinski, I. V. (2020). The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception. Biology Bulletin, 47(4), 407-416. https://doi.org/10.1134/S1062359020040020

Vancouver

Apryatin SA, Shipelin VA, Trusov NV, Mzhel’skaya KV, Kirbaeva NV, Soto JS и пр. The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception. Biology Bulletin. 2020 Июль 1;47(4):407-416. https://doi.org/10.1134/S1062359020040020

Author

Apryatin, S. A. ; Shipelin, V. A. ; Trusov, N. V. ; Mzhel’skaya, K. V. ; Kirbaeva, N. V. ; Soto, J. S. ; Riger, N. A. ; Gmoshinski, I. V. / The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception. в: Biology Bulletin. 2020 ; Том 47, № 4. стр. 407-416.

BibTeX

@article{34dd77e02fad4de897bd47e022b5ed27,
title = "The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception",
abstract = "Abstract: We studied the effects of quercetin (Q) on the behavioral responses and integral and metabolic indices in male db/db mice genetically predisposed to obesity and C57Bl/6J mice fed a diet with an excessive energy value. We examined forepaw grip strength, exploratory activity, anxiety, and short-term memory, as well as integral and biochemical indices, and the contents of leptin, ghrelin, and IL-10. We found differences between two models of obesity in the integral and biochemical indices and behavioral responses to Q treatment. In the db/db mice, they were associated with knockout of the Lepr gene encoding the leptin receptor, which prevented the neurotropic and regulatory functions of leptin. These effects of Q detected should be considered when justifying the dose and timing of this nutraceutical in clinical practice.",
author = "Apryatin, {S. A.} and Shipelin, {V. A.} and Trusov, {N. V.} and Mzhel{\textquoteright}skaya, {K. V.} and Kirbaeva, {N. V.} and Soto, {J. S.} and Riger, {N. A.} and Gmoshinski, {I. V.}",
year = "2020",
month = jul,
day = "1",
doi = "10.1134/S1062359020040020",
language = "English",
volume = "47",
pages = "407--416",
journal = "Biology Bulletin",
issn = "1062-3590",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "4",

}

RIS

TY - JOUR

T1 - The Effect of Quercetin on Metabolism and Behavioral Responses in Mice with Normal and Impaired Leptin Reception

AU - Apryatin, S. A.

AU - Shipelin, V. A.

AU - Trusov, N. V.

AU - Mzhel’skaya, K. V.

AU - Kirbaeva, N. V.

AU - Soto, J. S.

AU - Riger, N. A.

AU - Gmoshinski, I. V.

PY - 2020/7/1

Y1 - 2020/7/1

N2 - Abstract: We studied the effects of quercetin (Q) on the behavioral responses and integral and metabolic indices in male db/db mice genetically predisposed to obesity and C57Bl/6J mice fed a diet with an excessive energy value. We examined forepaw grip strength, exploratory activity, anxiety, and short-term memory, as well as integral and biochemical indices, and the contents of leptin, ghrelin, and IL-10. We found differences between two models of obesity in the integral and biochemical indices and behavioral responses to Q treatment. In the db/db mice, they were associated with knockout of the Lepr gene encoding the leptin receptor, which prevented the neurotropic and regulatory functions of leptin. These effects of Q detected should be considered when justifying the dose and timing of this nutraceutical in clinical practice.

AB - Abstract: We studied the effects of quercetin (Q) on the behavioral responses and integral and metabolic indices in male db/db mice genetically predisposed to obesity and C57Bl/6J mice fed a diet with an excessive energy value. We examined forepaw grip strength, exploratory activity, anxiety, and short-term memory, as well as integral and biochemical indices, and the contents of leptin, ghrelin, and IL-10. We found differences between two models of obesity in the integral and biochemical indices and behavioral responses to Q treatment. In the db/db mice, they were associated with knockout of the Lepr gene encoding the leptin receptor, which prevented the neurotropic and regulatory functions of leptin. These effects of Q detected should be considered when justifying the dose and timing of this nutraceutical in clinical practice.

UR - http://www.scopus.com/inward/record.url?scp=85088831540&partnerID=8YFLogxK

U2 - 10.1134/S1062359020040020

DO - 10.1134/S1062359020040020

M3 - Article

AN - SCOPUS:85088831540

VL - 47

SP - 407

EP - 416

JO - Biology Bulletin

JF - Biology Bulletin

SN - 1062-3590

IS - 4

ER -

ID: 115015929