TY - JOUR

T1 - Synthesis of 2-Mono- and 2,2-Bis[2-(1H-tetrazol-5-yl)ethyl] Derivatives of Dipterocarpol

AU - Rodionov, E I

AU - Kovaleva, A A

AU - Зорина, Алла Дмитриевна

AU - Старова, Галина Леонидовна

AU - Трифонов, Ростислав Евгеньевич

N1 - Funding Information: This study was performed under financial support by the Russian Foundation for Basic Research (project no. 17-04-00981-a).

PY - 2018/3

Y1 - 2018/3

N2 - The azidation of 2,2-bis(2-cyanoethyl)-20-hydroxydammar-24-en-3-one afforded new tetrazole derivatives of natural dipterocarpol, 2-(2-cyanoethyl)-2-[2-(1H-tetrazol-5-yl)ethyl]-20-hydroxydammar-24-en- 3-ones, 2,2-bis[2-(1H-tetrazol-5-yl)ethyl]-20-hydroxydammar-24-en-3-one, and 2,2-bis[2-(1H-tetrazol-5-yl)- ethyl]-3-oxo-25,26,27-trinordammaran-(20S),24-olide. The structure of the final and intermediate products was determined by NMR spectroscopy and X-ray analysis.

AB - The azidation of 2,2-bis(2-cyanoethyl)-20-hydroxydammar-24-en-3-one afforded new tetrazole derivatives of natural dipterocarpol, 2-(2-cyanoethyl)-2-[2-(1H-tetrazol-5-yl)ethyl]-20-hydroxydammar-24-en- 3-ones, 2,2-bis[2-(1H-tetrazol-5-yl)ethyl]-20-hydroxydammar-24-en-3-one, and 2,2-bis[2-(1H-tetrazol-5-yl)- ethyl]-3-oxo-25,26,27-trinordammaran-(20S),24-olide. The structure of the final and intermediate products was determined by NMR spectroscopy and X-ray analysis.

KW - ACID

KW - CHEMISTRY

KW - CYANOETHYL DERIVATIVES

KW - TRITERPENOIDS

UR - http://www.scopus.com/inward/record.url?scp=85048116402&partnerID=8YFLogxK

UR - http://link.springer.com/10.1134/S107042801803017X

UR - http://www.mendeley.com/research/synthesis-2mono-22bis21htetrazol5ylethyl-derivatives-dipterocarpol

U2 - 10.1134/S107042801803017X

DO - 10.1134/S107042801803017X

M3 - Article

VL - 54

SP - 485

EP - 489

JO - Russian Journal of Organic Chemistry

JF - Russian Journal of Organic Chemistry

SN - 1070-4280

IS - 3

ER -