Comparative data on structural-metabolic organization of cat's brain area 4 in normal conditions and after unilateral ocular enucleation are presented. The investigation was performed using histochemical demonstration of cytochrome oxidase activity. The data obtained were processed by computer methods using original device of image analysis. The results of the investigations indicate an uneven cytochrome oxidase distribution along sublayer IIIb of area 4 in unilaterally enucleated animals. On the basis of literature data it is suggested that such an alternation of areas of high and low reactivity is the evidence of ordering of retinal representation of right and left eyes in the sensomotor cortex.