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Sigma-1 receptor antagonists haloperidol and chlorpromazine modulate the effect of glutoxim on Na+ transport in frog skin. / A. V. Melnitskaya, ; Z. I. Krutetskaya; V. G. Antonov, ; A. D. Nozdrachev.

в: Doklady Biochemistry and Biophysics, Том 484, № 1, 01.05.2019, стр. 63-65.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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@article{fee42081b54d45a88c9c58165be2756c,
title = "Sigma-1 receptor antagonists haloperidol and chlorpromazine modulate the effect of glutoxim on Na+ transport in frog skin",
abstract = "Using voltage-clamp technique, the involvement of sigma-1 receptors in the regulation of Na+transport in frog skin by the immunomodulatory drug glutoxim was investigated. We have shown for the firsttime that preincubation of the frog skin with the sigma-1 receptor antagonists haloperidol and chlorpromazineattenuates the stimulatory effect of glutoxim on the Na+ transport. The results suggest the possibleinvolvement of the sigma-1 receptors in the regulation of Na+ transport in frog skin epithelium by glutoxim.DOI: 10.1134/S1607672919010186",
keywords = "sigma-1 receptor, immunomodulatory drug glutoxim, neuroleptics, Na+ transport,, CHANNEL, BINDING, DOMAINS",
author = "{A. V. Melnitskaya} and {Z. I. Krutetskaya} and {V. G. Antonov} and {A. D. Nozdrachev}",
year = "2019",
month = may,
day = "1",
doi = "10.1134/S1607672919010186",
language = "English",
volume = "484",
pages = "63--65",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Sigma-1 receptor antagonists haloperidol and chlorpromazine modulate the effect of glutoxim on Na+ transport in frog skin

AU - A. V. Melnitskaya, null

AU - Z. I. Krutetskaya, null

AU - V. G. Antonov, null

AU - A. D. Nozdrachev, null

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Using voltage-clamp technique, the involvement of sigma-1 receptors in the regulation of Na+transport in frog skin by the immunomodulatory drug glutoxim was investigated. We have shown for the firsttime that preincubation of the frog skin with the sigma-1 receptor antagonists haloperidol and chlorpromazineattenuates the stimulatory effect of glutoxim on the Na+ transport. The results suggest the possibleinvolvement of the sigma-1 receptors in the regulation of Na+ transport in frog skin epithelium by glutoxim.DOI: 10.1134/S1607672919010186

AB - Using voltage-clamp technique, the involvement of sigma-1 receptors in the regulation of Na+transport in frog skin by the immunomodulatory drug glutoxim was investigated. We have shown for the firsttime that preincubation of the frog skin with the sigma-1 receptor antagonists haloperidol and chlorpromazineattenuates the stimulatory effect of glutoxim on the Na+ transport. The results suggest the possibleinvolvement of the sigma-1 receptors in the regulation of Na+ transport in frog skin epithelium by glutoxim.DOI: 10.1134/S1607672919010186

KW - sigma-1 receptor, immunomodulatory drug glutoxim, neuroleptics, Na+ transport,

KW - CHANNEL

KW - BINDING

KW - DOMAINS

UR - http://www.scopus.com/inward/record.url?scp=85064817982&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/sigma1-receptor-antagonists-haloperidol-chlorpromazine-modulate-effect-glutoxim-na-transport-frog-s

U2 - 10.1134/S1607672919010186

DO - 10.1134/S1607672919010186

M3 - Article

VL - 484

SP - 63

EP - 65

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 41669272