Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Rh2(esp)2-Catalyzed Coupling of α-Diazo-γ-butyrolactams with Aromatic Amines. / Zhukovsky, Daniil; Dar'in, Dmitry; Krasavin, Mikhail.
в: European Journal of Organic Chemistry, Том 2019, № 27, 23.07.2019, стр. 4377-4383.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Rh2(esp)2-Catalyzed Coupling of α-Diazo-γ-butyrolactams with Aromatic Amines
AU - Zhukovsky, Daniil
AU - Dar'in, Dmitry
AU - Krasavin, Mikhail
PY - 2019/7/23
Y1 - 2019/7/23
N2 - Decomposition of α-diazo-γ-butyrolactams in the presence of aromatic and heteroaromatic amines, under Rh2(esp)2 catalysis, led to corresponding α-arylamino-γ-butyrolactams, which are of significant value for medicinal chemistry. The reaction scope encompasses primary as well as secondary, diversely substituted anilines and heteroaromatic amines. Insertion into the anilinic amino group was shown to be selective over amide and sulfonamide N–H insertion.
AB - Decomposition of α-diazo-γ-butyrolactams in the presence of aromatic and heteroaromatic amines, under Rh2(esp)2 catalysis, led to corresponding α-arylamino-γ-butyrolactams, which are of significant value for medicinal chemistry. The reaction scope encompasses primary as well as secondary, diversely substituted anilines and heteroaromatic amines. Insertion into the anilinic amino group was shown to be selective over amide and sulfonamide N–H insertion.
KW - Amimnes
KW - Homogeneous catalysis
KW - Lactams
KW - N–H insertion
KW - ORGANIC-SYNTHESIS
KW - DESIGN
KW - N-H insertion
KW - N-H BONDS
KW - POTENT
KW - CARBONIC-ANHYDRASE IX
KW - CARBENE INSERTION
KW - INHIBITORS
KW - SELECTIVITY
UR - http://www.scopus.com/inward/record.url?scp=85068082114&partnerID=8YFLogxK
UR - http://www.mendeley.com/research/rh2esp2catalyzed-coupling-%CE%B1diazo%CE%B3butyrolactams-aromatic-amines
U2 - 10.1002/ejoc.201900565
DO - 10.1002/ejoc.201900565
M3 - Article
AN - SCOPUS:85068082114
VL - 2019
SP - 4377
EP - 4383
JO - European Journal of Organic Chemistry
JF - European Journal of Organic Chemistry
SN - 1434-193X
IS - 27
ER -
ID: 46204034