Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy

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Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy. / Ustabaev, P. Sh.; Zykova, P. D.; Bakhmetev, V. V.; Leonova, E. I.

в: Russian Journal of Bioorganic Chemistry, Том 50, № 2, 01.04.2024, стр. 522-529.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

BibTeX

@article{9de3b5117f34491aadf4fd92329b3dce,

title = "Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy",

abstract = "Objective: GdF3:Tb nanosized phosphors were synthesized by the sol–gel and hydrothermal methods. Directed crystallite growth toward the (020) and (210) crystallographic planes was revealed. Methods: The chemical trap method was used to explore the efficiency of reactive oxygen production of the GdF3:Tb–Rose Bengal photosensitizer system. Results and Discussion: It was shown that the phosphors synthesized by the hydrothermal method have a smaller particle size and a higher luminescence intensity compared to those synthesized by the sol–gel method. Due to their luminescent characteristics and particle size, the GdF3:Tb nanosized phosphors synthesized by the hydrothermal method are suitable for use, in combination with the Rose Bengal photosensitizer, in drug formulations for X-ray photodynamic therapy of oncological diseases. Conclusions: The addition of the GdF3:Tb nanosized phosphors, synthesized by the hydrothermal method, significantly (by 17%) increases the production of reactive oxygen.",

keywords = "GdF3:Tb, X-ray photodynamic therapy, active oxygen, hydrothermal method, nanosized phosphors, sol–gel method",

author = "Ustabaev, {P. Sh.} and Zykova, {P. D.} and Bakhmetev, {V. V.} and Leonova, {E. I.}",

year = "2024",

month = apr,

day = "1",

doi = "10.1134/s1068162024020894",

language = "English",

volume = "50",

pages = "522--529",

journal = "Russian Journal of Bioorganic Chemistry",

issn = "1068-1620",

publisher = "МАИК {"}Наука/Интерпериодика{"}",

number = "2",

}

RIS

TY - JOUR

T1 - Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy

AU - Ustabaev, P. Sh.

AU - Zykova, P. D.

AU - Bakhmetev, V. V.

AU - Leonova, E. I.

PY - 2024/4/1

Y1 - 2024/4/1

N2 - Objective: GdF3:Tb nanosized phosphors were synthesized by the sol–gel and hydrothermal methods. Directed crystallite growth toward the (020) and (210) crystallographic planes was revealed. Methods: The chemical trap method was used to explore the efficiency of reactive oxygen production of the GdF3:Tb–Rose Bengal photosensitizer system. Results and Discussion: It was shown that the phosphors synthesized by the hydrothermal method have a smaller particle size and a higher luminescence intensity compared to those synthesized by the sol–gel method. Due to their luminescent characteristics and particle size, the GdF3:Tb nanosized phosphors synthesized by the hydrothermal method are suitable for use, in combination with the Rose Bengal photosensitizer, in drug formulations for X-ray photodynamic therapy of oncological diseases. Conclusions: The addition of the GdF3:Tb nanosized phosphors, synthesized by the hydrothermal method, significantly (by 17%) increases the production of reactive oxygen.

AB - Objective: GdF3:Tb nanosized phosphors were synthesized by the sol–gel and hydrothermal methods. Directed crystallite growth toward the (020) and (210) crystallographic planes was revealed. Methods: The chemical trap method was used to explore the efficiency of reactive oxygen production of the GdF3:Tb–Rose Bengal photosensitizer system. Results and Discussion: It was shown that the phosphors synthesized by the hydrothermal method have a smaller particle size and a higher luminescence intensity compared to those synthesized by the sol–gel method. Due to their luminescent characteristics and particle size, the GdF3:Tb nanosized phosphors synthesized by the hydrothermal method are suitable for use, in combination with the Rose Bengal photosensitizer, in drug formulations for X-ray photodynamic therapy of oncological diseases. Conclusions: The addition of the GdF3:Tb nanosized phosphors, synthesized by the hydrothermal method, significantly (by 17%) increases the production of reactive oxygen.

KW - GdF3:Tb

KW - X-ray photodynamic therapy

KW - active oxygen

KW - hydrothermal method

KW - nanosized phosphors

KW - sol–gel method

UR - https://www.mendeley.com/catalogue/e871e514-3af4-3fd5-82da-1c3c18f38df9/

U2 - 10.1134/s1068162024020894

DO - 10.1134/s1068162024020894

M3 - Article

VL - 50

SP - 522

EP - 529

JO - Russian Journal of Bioorganic Chemistry

JF - Russian Journal of Bioorganic Chemistry

SN - 1068-1620

IS - 2

ER -

ID: 120144320