Research output: Contribution to journal › Article › peer-review
Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy. / Ustabaev, P. Sh.; Zykova, P. D.; Bakhmetev, V. V.; Leonova, E. I.
In: Russian Journal of Bioorganic Chemistry, Vol. 50, No. 2, 01.04.2024, p. 522-529.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Research and Optimization of the Synthesis of GdF3:Tb X-Ray Phosphors for X-Ray Photodynamic Therapy
AU - Ustabaev, P. Sh.
AU - Zykova, P. D.
AU - Bakhmetev, V. V.
AU - Leonova, E. I.
PY - 2024/4/1
Y1 - 2024/4/1
N2 - Objective: GdF3:Tb nanosized phosphors were synthesized by the sol–gel and hydrothermal methods. Directed crystallite growth toward the (020) and (210) crystallographic planes was revealed. Methods: The chemical trap method was used to explore the efficiency of reactive oxygen production of the GdF3:Tb–Rose Bengal photosensitizer system. Results and Discussion: It was shown that the phosphors synthesized by the hydrothermal method have a smaller particle size and a higher luminescence intensity compared to those synthesized by the sol–gel method. Due to their luminescent characteristics and particle size, the GdF3:Tb nanosized phosphors synthesized by the hydrothermal method are suitable for use, in combination with the Rose Bengal photosensitizer, in drug formulations for X-ray photodynamic therapy of oncological diseases. Conclusions: The addition of the GdF3:Tb nanosized phosphors, synthesized by the hydrothermal method, significantly (by 17%) increases the production of reactive oxygen.
AB - Objective: GdF3:Tb nanosized phosphors were synthesized by the sol–gel and hydrothermal methods. Directed crystallite growth toward the (020) and (210) crystallographic planes was revealed. Methods: The chemical trap method was used to explore the efficiency of reactive oxygen production of the GdF3:Tb–Rose Bengal photosensitizer system. Results and Discussion: It was shown that the phosphors synthesized by the hydrothermal method have a smaller particle size and a higher luminescence intensity compared to those synthesized by the sol–gel method. Due to their luminescent characteristics and particle size, the GdF3:Tb nanosized phosphors synthesized by the hydrothermal method are suitable for use, in combination with the Rose Bengal photosensitizer, in drug formulations for X-ray photodynamic therapy of oncological diseases. Conclusions: The addition of the GdF3:Tb nanosized phosphors, synthesized by the hydrothermal method, significantly (by 17%) increases the production of reactive oxygen.
KW - GdF3:Tb
KW - X-ray photodynamic therapy
KW - active oxygen
KW - hydrothermal method
KW - nanosized phosphors
KW - sol–gel method
UR - https://www.mendeley.com/catalogue/e871e514-3af4-3fd5-82da-1c3c18f38df9/
U2 - 10.1134/s1068162024020894
DO - 10.1134/s1068162024020894
M3 - Article
VL - 50
SP - 522
EP - 529
JO - Russian Journal of Bioorganic Chemistry
JF - Russian Journal of Bioorganic Chemistry
SN - 1068-1620
IS - 2
ER -
ID: 120144320