Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Protective action of water-soluble fullerene adducts on the example of an adduct with L-arginine. / Шаройко, Владимир Владимирович; Кукалия, Олеги Нугзарович; Дарвиш, Диана; Мещеряков, Анатолий Анатольевич ; Юрьев, Глеб Олегович; Андоскин, Павел; Пенькова, Анастасия Владимировна; Агеев, Сергей Вадимович; Петухова, Н.В.; Тимощук, Кирилл Владимирович; Петров, Андрей Витальевич; Акентьев, Александр Владимирович; Нерух, Дмитрий; Мазур, Антон Станиславович; Майстренко, Дмитрий Николаевич; Молчанов, Олег Евгеньевич; Мурин, Игорь Васильевич; Семёнов, Константин Николаевич.
в: Journal of Molecular Liquids, Том 401, 124702, 01.05.2024.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Protective action of water-soluble fullerene adducts on the example of an adduct with L-arginine
AU - Шаройко, Владимир Владимирович
AU - Кукалия, Олеги Нугзарович
AU - Дарвиш, Диана
AU - Мещеряков, Анатолий Анатольевич
AU - Юрьев, Глеб Олегович
AU - Андоскин, Павел
AU - Пенькова, Анастасия Владимировна
AU - Агеев, Сергей Вадимович
AU - Петухова, Н.В.
AU - Тимощук, Кирилл Владимирович
AU - Петров, Андрей Витальевич
AU - Акентьев, Александр Владимирович
AU - Нерух, Дмитрий
AU - Мазур, Антон Станиславович
AU - Майстренко, Дмитрий Николаевич
AU - Молчанов, Олег Евгеньевич
AU - Мурин, Игорь Васильевич
AU - Семёнов, Константин Николаевич
PY - 2024/5/1
Y1 - 2024/5/1
N2 - We present radioprotective, antiglycating, and photoprotective properties of a water-soluble C60 fullerene derivative with L-arginine (C60-Arg) and composite films based on collagen containing C60-Arg. The synthesis of these materials is described. The identification of the synthesised materials was carried out using modern physicochemical methods of analysis. The physicochemical properties of aqueous solutions of C60-Arg, such as, particle size distribution, zeta potentials, distribution coefficient in the octan-1-ol–water system were measured. The computer simulation of the process of C60-Arg association in aqueous and isotonic solutions was carried out using Molecular Dynamics. Composite films based on collagen containing C60-Arg demonstrate significant improvement in mechanical properties, cell adhesion, and cell proliferation when the nano-modifier is added. This shows high potential for the use of the C60-Arg adduct in biomedicine.
AB - We present radioprotective, antiglycating, and photoprotective properties of a water-soluble C60 fullerene derivative with L-arginine (C60-Arg) and composite films based on collagen containing C60-Arg. The synthesis of these materials is described. The identification of the synthesised materials was carried out using modern physicochemical methods of analysis. The physicochemical properties of aqueous solutions of C60-Arg, such as, particle size distribution, zeta potentials, distribution coefficient in the octan-1-ol–water system were measured. The computer simulation of the process of C60-Arg association in aqueous and isotonic solutions was carried out using Molecular Dynamics. Composite films based on collagen containing C60-Arg demonstrate significant improvement in mechanical properties, cell adhesion, and cell proliferation when the nano-modifier is added. This shows high potential for the use of the C60-Arg adduct in biomedicine.
KW - Collagen
KW - Fullerene
KW - Molecular Dynamics
KW - Photoprotector
KW - Radioprotector
UR - https://www.mendeley.com/catalogue/f138c187-65d7-3765-b4f3-ee3f6622c898/
U2 - 10.1016/j.molliq.2024.124702
DO - 10.1016/j.molliq.2024.124702
M3 - Article
VL - 401
JO - Journal of Molecular Liquids
JF - Journal of Molecular Liquids
SN - 0167-7322
M1 - 124702
ER -
ID: 121394429