Research output: Contribution to journal › Article › peer-review
Protective action of water-soluble fullerene adducts on the example of an adduct with L-arginine. / Шаройко, Владимир Владимирович; Kukaliia, Olegi N.; Darvish, D. M.; Meshcheriakov, Anatolii A.; Iurev, Gleb O.; Andoskin, Pavel A.; Пенькова, Анастасия Владимировна; Агеев, Сергей Вадимович; Petukhova, N.; Тимощук, Кирилл Владимирович; Петров, Андрей Витальевич; Акентьев, Александр Владимирович.
In: Journal of Molecular Liquids, Vol. 401, 124702, 01.05.2024.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Protective action of water-soluble fullerene adducts on the example of an adduct with L-arginine
AU - Шаройко, Владимир Владимирович
AU - Kukaliia, Olegi N.
AU - Darvish, D. M.
AU - Meshcheriakov, Anatolii A.
AU - Iurev, Gleb O.
AU - Andoskin, Pavel A.
AU - Пенькова, Анастасия Владимировна
AU - Агеев, Сергей Вадимович
AU - Petukhova, N.
AU - Тимощук, Кирилл Владимирович
AU - Петров, Андрей Витальевич
AU - Акентьев, Александр Владимирович
PY - 2024/5/1
Y1 - 2024/5/1
N2 - We present radioprotective, antiglycating, and photoprotective properties of a water-soluble C60 fullerene derivative with L-arginine (C60-Arg) and composite films based on collagen containing C60-Arg. The synthesis of these materials is described. The identification of the synthesised materials was carried out using modern physicochemical methods of analysis. The physicochemical properties of aqueous solutions of C60-Arg, such as, particle size distribution, zeta potentials, distribution coefficient in the octan-1-ol–water system were measured. The computer simulation of the process of C60-Arg association in aqueous and isotonic solutions was carried out using Molecular Dynamics. Composite films based on collagen containing C60-Arg demonstrate significant improvement in mechanical properties, cell adhesion, and cell proliferation when the nano-modifier is added. This shows high potential for the use of the C60-Arg adduct in biomedicine.
AB - We present radioprotective, antiglycating, and photoprotective properties of a water-soluble C60 fullerene derivative with L-arginine (C60-Arg) and composite films based on collagen containing C60-Arg. The synthesis of these materials is described. The identification of the synthesised materials was carried out using modern physicochemical methods of analysis. The physicochemical properties of aqueous solutions of C60-Arg, such as, particle size distribution, zeta potentials, distribution coefficient in the octan-1-ol–water system were measured. The computer simulation of the process of C60-Arg association in aqueous and isotonic solutions was carried out using Molecular Dynamics. Composite films based on collagen containing C60-Arg demonstrate significant improvement in mechanical properties, cell adhesion, and cell proliferation when the nano-modifier is added. This shows high potential for the use of the C60-Arg adduct in biomedicine.
KW - Collagen
KW - Fullerene
KW - Molecular Dynamics
KW - Photoprotector
KW - Radioprotector
UR - https://www.mendeley.com/catalogue/f138c187-65d7-3765-b4f3-ee3f6622c898/
U2 - 10.1016/j.molliq.2024.124702
DO - 10.1016/j.molliq.2024.124702
M3 - Article
VL - 401
JO - Journal of Molecular Liquids
JF - Journal of Molecular Liquids
SN - 0167-7322
M1 - 124702
ER -
ID: 121394429