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Probing the conjugation of gold NPs using single- stranded DNA comprising two polyadenine adhesive tails. / Соколов, Петр Александрович; Рамазанов, Руслан Рафядинович.

в: Journal of Adhesion, 06.03.2022.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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@article{403e3fd9b1c94033805e5fbb2603d50a,
title = "Probing the conjugation of gold NPs using single- stranded DNA comprising two polyadenine adhesive tails",
abstract = "The spatial arrangement of nanoobjects by using DNA is a promising nano-design technology. Polyadenine adhesive tails are increasingly used to anchor functional oligonucleotides on the surface of gold nanoparticles at low pH. Further hybridization of such functional oligonucleotides allows nanoparticles to be organized within the desired design. In this work, we studied the effect of temperature, ionic strength, and strand design on the adsorption rate of polyadenines on the surface of gold nanoparticles at different pH. We found that there are temperature and ionic strength ranges in which the adsorption rate increases and vice versa. There are also significant differences in the effects of monovalent sodium and divalent magnesium ions. We have shown that dual-tail DNA strand design allows for increased surface density, which is significantly higher than that obtained with the standard one-tail strand design.",
keywords = "ATP aptamer, DNA, biosensor, conjugation, gold nanoparticles, polyadenine, FUNCTIONALIZATION, NANOPARTICLES, NONTHIOLATED DNA, ADSORPTION",
author = "Соколов, {Петр Александрович} and Рамазанов, {Руслан Рафядинович}",
note = "Publisher Copyright: {\textcopyright} 2022 Taylor & Francis Group, LLC.",
year = "2022",
month = mar,
day = "6",
doi = "10.1080/00218464.2022.2047942",
language = "English",
journal = "Journal of Adhesion",
issn = "0021-8464",
publisher = "Taylor & Francis",

}

RIS

TY - JOUR

T1 - Probing the conjugation of gold NPs using single- stranded DNA comprising two polyadenine adhesive tails

AU - Соколов, Петр Александрович

AU - Рамазанов, Руслан Рафядинович

N1 - Publisher Copyright: © 2022 Taylor & Francis Group, LLC.

PY - 2022/3/6

Y1 - 2022/3/6

N2 - The spatial arrangement of nanoobjects by using DNA is a promising nano-design technology. Polyadenine adhesive tails are increasingly used to anchor functional oligonucleotides on the surface of gold nanoparticles at low pH. Further hybridization of such functional oligonucleotides allows nanoparticles to be organized within the desired design. In this work, we studied the effect of temperature, ionic strength, and strand design on the adsorption rate of polyadenines on the surface of gold nanoparticles at different pH. We found that there are temperature and ionic strength ranges in which the adsorption rate increases and vice versa. There are also significant differences in the effects of monovalent sodium and divalent magnesium ions. We have shown that dual-tail DNA strand design allows for increased surface density, which is significantly higher than that obtained with the standard one-tail strand design.

AB - The spatial arrangement of nanoobjects by using DNA is a promising nano-design technology. Polyadenine adhesive tails are increasingly used to anchor functional oligonucleotides on the surface of gold nanoparticles at low pH. Further hybridization of such functional oligonucleotides allows nanoparticles to be organized within the desired design. In this work, we studied the effect of temperature, ionic strength, and strand design on the adsorption rate of polyadenines on the surface of gold nanoparticles at different pH. We found that there are temperature and ionic strength ranges in which the adsorption rate increases and vice versa. There are also significant differences in the effects of monovalent sodium and divalent magnesium ions. We have shown that dual-tail DNA strand design allows for increased surface density, which is significantly higher than that obtained with the standard one-tail strand design.

KW - ATP aptamer

KW - DNA

KW - biosensor

KW - conjugation

KW - gold nanoparticles

KW - polyadenine

KW - FUNCTIONALIZATION

KW - NANOPARTICLES

KW - NONTHIOLATED DNA

KW - ADSORPTION

UR - http://www.scopus.com/inward/record.url?scp=85126046487&partnerID=8YFLogxK

UR - https://www.tandfonline.com/doi/full/10.1080/00218464.2022.2047942

UR - https://www.mendeley.com/catalogue/0a705c72-fa44-33cf-aaf2-de451371a861/

U2 - 10.1080/00218464.2022.2047942

DO - 10.1080/00218464.2022.2047942

M3 - Article

JO - Journal of Adhesion

JF - Journal of Adhesion

SN - 0021-8464

ER -

ID: 93245780