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Phospholipase A2 inhibitors modulate the effect of trifluoperazine on the intracellular Ca2+ concentration in macrophages. / Krutetskaya, Z. I. ; Milenina, L. S.; Naumova, A. A. ; Butov, S. N. ; Antonov, V. G. ; Nozdrachev, A. D. .

в: Doklady Biochemistry and Biophysics, Том 478, № 1, 2018, стр. 41-43.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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@article{4e1ad5e99bc84aeeb9530af52964e47c,
title = "Phospholipase A2 inhibitors modulate the effect of trifluoperazine on the intracellular Ca2+ concentration in macrophages",
abstract = "Using Fura-2AM microfluorimetry, it was shown for the first time that phospholipase A 2 inhibitors 4-bromophenacyl bromide and glucocorticosteroids prednisolone and dexamethasone attenuate Ca 2+ responses induced by neuroleptic trifluoperazine in macrophages. The results suggest the involvement of phospholipase A 2 and arachidonic acid metabolism cascade in the effect of trifluoperazine on intracellular Ca 2+ concentration in macrophages. ",
keywords = "ACTIVATION, CELLS, PHENOTHIAZINES",
author = "Krutetskaya, {Z. I.} and Milenina, {L. S.} and Naumova, {A. A.} and Butov, {S. N.} and Antonov, {V. G.} and Nozdrachev, {A. D.}",
note = "Krutetskaya Z.I., Milenina L. S., Naumova A.A., Butov S.N., Antonov V.G., Nozdrachev A.D. 2018. Phospholipase A2 inhibitors modulate the effect of trifluoperazine on the intracellular Ca2+ concentration in macrophages. Doklady Biochemistry and Biophysics. 478: 1 - 3.",
year = "2018",
doi = "10.1134/S1607672918010118",
language = "English",
volume = "478",
pages = "41--43",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Phospholipase A2 inhibitors modulate the effect of trifluoperazine on the intracellular Ca2+ concentration in macrophages

AU - Krutetskaya, Z. I.

AU - Milenina, L. S.

AU - Naumova, A. A.

AU - Butov, S. N.

AU - Antonov, V. G.

AU - Nozdrachev, A. D.

N1 - Krutetskaya Z.I., Milenina L. S., Naumova A.A., Butov S.N., Antonov V.G., Nozdrachev A.D. 2018. Phospholipase A2 inhibitors modulate the effect of trifluoperazine on the intracellular Ca2+ concentration in macrophages. Doklady Biochemistry and Biophysics. 478: 1 - 3.

PY - 2018

Y1 - 2018

N2 - Using Fura-2AM microfluorimetry, it was shown for the first time that phospholipase A 2 inhibitors 4-bromophenacyl bromide and glucocorticosteroids prednisolone and dexamethasone attenuate Ca 2+ responses induced by neuroleptic trifluoperazine in macrophages. The results suggest the involvement of phospholipase A 2 and arachidonic acid metabolism cascade in the effect of trifluoperazine on intracellular Ca 2+ concentration in macrophages.

AB - Using Fura-2AM microfluorimetry, it was shown for the first time that phospholipase A 2 inhibitors 4-bromophenacyl bromide and glucocorticosteroids prednisolone and dexamethasone attenuate Ca 2+ responses induced by neuroleptic trifluoperazine in macrophages. The results suggest the involvement of phospholipase A 2 and arachidonic acid metabolism cascade in the effect of trifluoperazine on intracellular Ca 2+ concentration in macrophages.

KW - ACTIVATION

KW - CELLS

KW - PHENOTHIAZINES

UR - http://www.scopus.com/inward/record.url?scp=85043979249&partnerID=8YFLogxK

U2 - 10.1134/S1607672918010118

DO - 10.1134/S1607672918010118

M3 - Article

VL - 478

SP - 41

EP - 43

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 16217496