In this study the maghemite nanoparticles have been obtained via application of original approach within hydrothermal synthesis method. The morphology parameters have been determined by a number of methods including XRD, TEM and specific surface area estimation (the BET model). The magnetic properties of the nanoparticles have been measured using VSM that confirmed superparamagnetic behavior of the powder at 300 K with the blocking temperature value near 80 K. The aqueous suspensions of the obtained nanoparticles have been studied by DLS method; their temporal stability has been evaluated. The analysis of relaxation times in model system has shown their applicability as a MRI contrast agent. In order to turn the obtained nanoparticles into dosage form two approaches have been studied: covering their surface with model protein and encapsulation of the nanoparticles into a polymer nanocontainer.