Результаты исследований: Научные публикации в периодических изданиях › статья
Fluoroaziridines as novel substrates in the modified Petasis reaction: synthesis of monofluorinated propargyl amines. / Konev, A.S.; Stas, S.; Novikov, M.S.; Khlebnikov, A.F.; Tehrani, K. Abbaspour.
в: Tetrahedron, № 1, 2008, стр. 117-123.Результаты исследований: Научные публикации в периодических изданиях › статья
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TY - JOUR
T1 - Fluoroaziridines as novel substrates in the modified Petasis reaction: synthesis of monofluorinated propargyl amines
AU - Konev, A.S.
AU - Stas, S.
AU - Novikov, M.S.
AU - Khlebnikov, A.F.
AU - Tehrani, K. Abbaspour
PY - 2008
Y1 - 2008
N2 - Reaction of 2-fluoroaziridines with potassium alkynyltrifluoroborates in the presence of BF3·OEt2 leads to fluorinated propargyl amines in moderate to good yields. The reaction proceeds as an in situ isomerization of 2-fluoroaziridines to α-fluorinated imines, followed by the reaction of the imine with alkynyldifluoroborane, which is generated in situ from the potassium alkynyltrifluoroborates and BF3·OEt2. © 2007 Elsevier Ltd. All rights reserved.
AB - Reaction of 2-fluoroaziridines with potassium alkynyltrifluoroborates in the presence of BF3·OEt2 leads to fluorinated propargyl amines in moderate to good yields. The reaction proceeds as an in situ isomerization of 2-fluoroaziridines to α-fluorinated imines, followed by the reaction of the imine with alkynyldifluoroborane, which is generated in situ from the potassium alkynyltrifluoroborates and BF3·OEt2. © 2007 Elsevier Ltd. All rights reserved.
M3 - Article
SP - 117
EP - 123
JO - Tetrahedron
JF - Tetrahedron
SN - 0040-4020
IS - 1
ER -
ID: 5009863