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BDNF Val66Met and cognition : All, none, or some? A meta-analysis of the genetic association. / Mandelman, S. D.; Grigorenko, E. L.

в: Genes, Brain and Behavior, Том 11, № 2, 03.2012, стр. 127-136.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Mandelman, S. D. ; Grigorenko, E. L. / BDNF Val66Met and cognition : All, none, or some? A meta-analysis of the genetic association. в: Genes, Brain and Behavior. 2012 ; Том 11, № 2. стр. 127-136.

BibTeX

@article{399be47eb06b4fa9b64171474a1150d5,
title = "BDNF Val66Met and cognition: All, none, or some? A meta-analysis of the genetic association",
abstract = "The Val66Met, G196A (rs6265) polymorphism in the brain-derived neurotrophic factor gene, BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet, the pattern of results is complex and conflicting. In this study, we conducted a meta-analysis that included 23 publications containing 31 independent samples comprised of 7095 individuals. The phenotypes that were examined in this analysis covered a wide variety of cognitive functions and included indicators of general cognitive ability, memory, executive function, visual processing skills and cognitive fluency. The meta-analysis did not establish significant genetic associations between the Val66Met polymorphism and any of the phenotypes that were included.",
keywords = "BDNF, Cognition, Cognitive indicators, Genetic association, Rs6525, Val66Met",
author = "Mandelman, {S. D.} and Grigorenko, {E. L.}",
year = "2012",
month = mar,
doi = "10.1111/j.1601-183X.2011.00738.x",
language = "English",
volume = "11",
pages = "127--136",
journal = "Genes, Brain and Behavior",
issn = "1601-1848",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - BDNF Val66Met and cognition

T2 - All, none, or some? A meta-analysis of the genetic association

AU - Mandelman, S. D.

AU - Grigorenko, E. L.

PY - 2012/3

Y1 - 2012/3

N2 - The Val66Met, G196A (rs6265) polymorphism in the brain-derived neurotrophic factor gene, BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet, the pattern of results is complex and conflicting. In this study, we conducted a meta-analysis that included 23 publications containing 31 independent samples comprised of 7095 individuals. The phenotypes that were examined in this analysis covered a wide variety of cognitive functions and included indicators of general cognitive ability, memory, executive function, visual processing skills and cognitive fluency. The meta-analysis did not establish significant genetic associations between the Val66Met polymorphism and any of the phenotypes that were included.

AB - The Val66Met, G196A (rs6265) polymorphism in the brain-derived neurotrophic factor gene, BDNF, located at 11p13, has been associated with a wide range of cognitive functions. Yet, the pattern of results is complex and conflicting. In this study, we conducted a meta-analysis that included 23 publications containing 31 independent samples comprised of 7095 individuals. The phenotypes that were examined in this analysis covered a wide variety of cognitive functions and included indicators of general cognitive ability, memory, executive function, visual processing skills and cognitive fluency. The meta-analysis did not establish significant genetic associations between the Val66Met polymorphism and any of the phenotypes that were included.

KW - BDNF

KW - Cognition

KW - Cognitive indicators

KW - Genetic association

KW - Rs6525

KW - Val66Met

UR - http://www.scopus.com/inward/record.url?scp=84856319161&partnerID=8YFLogxK

U2 - 10.1111/j.1601-183X.2011.00738.x

DO - 10.1111/j.1601-183X.2011.00738.x

M3 - Article

C2 - 21980924

AN - SCOPUS:84856319161

VL - 11

SP - 127

EP - 136

JO - Genes, Brain and Behavior

JF - Genes, Brain and Behavior

SN - 1601-1848

IS - 2

ER -

ID: 87392574