The study explores the opportunities of implementation knowledge management tools in the development and assessment of employees in high tech industries in Russia. The main issues that authors explore are revealed on the base of the personnel audit in such sectors as nanoelectronics, nanophotonics, and nanopolymers. These issues include the choice of the technology that identifies what qualifications miss in the context of companies' business processes; the analysis of the labor market (fluctuations of salaries, the concept of job status, expectations towards employers, the link between demand and supply, the dynamics of the ratio of CVs and vacancies, the rating of employers' requests); the determination of the employee market value; the setting for professional standards; the analysis of qualification assessment systems applied in the sector; the organization of independent qualifications assessment; the organization of a network expert community. The case study of Komsomolskaya Pravda Plant, one of the oldest Russian plastics processing companies, is implemented, and the development of the advanced training is proposed as the solution of key problems.