Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. / Галенко, Екатерина Евгениевна; Хлебников, Александр Феодосиевич; Новиков, Михаил Сергеевич; Занахов, Тимур Олегович.
в: Beilstein Journal of Organic Chemistry, Том 18, 23.06.2022, стр. 738-745.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates
AU - Галенко, Екатерина Евгениевна
AU - Хлебников, Александр Феодосиевич
AU - Новиков, Михаил Сергеевич
AU - Занахов, Тимур Олегович
N1 - Publisher Copyright: © 2022 Zanakhov et al.
PY - 2022/6/23
Y1 - 2022/6/23
N2 - A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO) 6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyridine-3-carboxylates synthesized provide easy access to 2,4,6-triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates.
AB - A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO) 6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyridine-3-carboxylates synthesized provide easy access to 2,4,6-triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates.
KW - 4-pyridone
KW - isoxazole
KW - methyl nicotinate
KW - molybdenum hexacarbonyl
KW - ring expansion
UR - http://www.scopus.com/inward/record.url?scp=85136538295&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/77221205-ffaa-3379-b7f8-8fb97e93698c/
U2 - 10.3762/bjoc.18.74
DO - 10.3762/bjoc.18.74
M3 - Article
C2 - 35821697
VL - 18
SP - 738
EP - 745
JO - Beilstein Journal of Organic Chemistry
JF - Beilstein Journal of Organic Chemistry
SN - 1860-5397
ER -
ID: 98529388