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An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. / Галенко, Екатерина Евгениевна; Хлебников, Александр Феодосиевич; Новиков, Михаил Сергеевич; Занахов, Тимур Олегович.

In: Beilstein Journal of Organic Chemistry, Vol. 18, 23.06.2022, p. 738-745.

Research output: Contribution to journal › Article › peer-review

Harvard

Галенко, ЕЕ, Хлебников, АФ, Новиков, МС & Занахов, ТО 2022, 'An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates', Beilstein Journal of Organic Chemistry, vol. 18, pp. 738-745. https://doi.org/10.3762/bjoc.18.74

APA

Галенко, Е. Е., Хлебников, А. Ф., Новиков, М. С., & Занахов, Т. О. (2022). An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. Beilstein Journal of Organic Chemistry, 18, 738-745. https://doi.org/10.3762/bjoc.18.74

Vancouver

Галенко ЕЕ, Хлебников АФ, Новиков МС, Занахов ТО. An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. Beilstein Journal of Organic Chemistry. 2022 Jun 23;18:738-745. https://doi.org/10.3762/bjoc.18.74

Author

Галенко, Екатерина Евгениевна ; Хлебников, Александр Феодосиевич ; Новиков, Михаил Сергеевич ; Занахов, Тимур Олегович. / An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates. In: Beilstein Journal of Organic Chemistry. 2022 ; Vol. 18. pp. 738-745.

BibTeX

@article{c9abab79b8cf4de89fbc5130386bd5c4,
title = "An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates",
abstract = "A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO) 6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyridine-3-carboxylates synthesized provide easy access to 2,4,6-triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates. ",
keywords = "4-pyridone, isoxazole, methyl nicotinate, molybdenum hexacarbonyl, ring expansion",
author = "Галенко, {Екатерина Евгениевна} and Хлебников, {Александр Феодосиевич} and Новиков, {Михаил Сергеевич} and Занахов, {Тимур Олегович}",
note = "Publisher Copyright: {\textcopyright} 2022 Zanakhov et al.",
year = "2022",
month = jun,
day = "23",
doi = "10.3762/bjoc.18.74",
language = "English",
volume = "18",
pages = "738--745",
journal = "Beilstein Journal of Organic Chemistry",
issn = "1860-5397",
publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

RIS

TY - JOUR

T1 - An isoxazole strategy for the synthesis of 4-oxo-1,4-dihydropyridine-3-carboxylates

AU - Галенко, Екатерина Евгениевна

AU - Хлебников, Александр Феодосиевич

AU - Новиков, Михаил Сергеевич

AU - Занахов, Тимур Олегович

N1 - Publisher Copyright: © 2022 Zanakhov et al.

PY - 2022/6/23

Y1 - 2022/6/23

N2 - A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO) 6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyridine-3-carboxylates synthesized provide easy access to 2,4,6-triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates.

AB - A method has been developed for the preparation of 2-alkyl-6-aryl-, 2-aryl-6-aryl and 2,6-diaryl-5-aryl/hetaryl-substituted methyl 4-oxo-1,4-dihydropyridine-3-carboxylates by Mo(CO) 6-mediated ring expansion of methyl 2-(isoxazol-5-yl)-3-oxopropanoates. The high reactivity of 4-oxo-1,4-dihydropyridine-3-carboxylates synthesized provide easy access to 2,4,6-triaryl-substituted and 1,2,5,6-tetrasubstituted nicotinates.

KW - 4-pyridone

KW - isoxazole

KW - methyl nicotinate

KW - molybdenum hexacarbonyl

KW - ring expansion

UR - http://www.scopus.com/inward/record.url?scp=85136538295&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/77221205-ffaa-3379-b7f8-8fb97e93698c/

U2 - 10.3762/bjoc.18.74

DO - 10.3762/bjoc.18.74

M3 - Article

C2 - 35821697

VL - 18

SP - 738

EP - 745

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

SN - 1860-5397

ER -

ID: 98529388