Standard

A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene : This article belongs to the Special Issue Synthesis of Bioactive Compounds. / Аксенов, Николай; Куренков, Игорь; Арутюнов, Николай; Малюга, Владимир; Аксенов, Дмитрий ; Момотова, Дарья; Зацепилина, Анна; Чуканова, Елизавета Александровна; Леонтьев, Александр; Аксенов, Александр.

в: Molecules, Том 28, № 9, 3657, 23.04.2023.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Аксенов, Н, Куренков, И, Арутюнов, Н, Малюга, В, Аксенов, Д, Момотова, Д, Зацепилина, А, Чуканова, ЕА, Леонтьев, А & Аксенов, А 2023, 'A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene: This article belongs to the Special Issue Synthesis of Bioactive Compounds', Molecules, Том. 28, № 9, 3657. https://doi.org/10.3390/molecules28093657

APA

Аксенов, Н., Куренков, И., Арутюнов, Н., Малюга, В., Аксенов, Д., Момотова, Д., Зацепилина, А., Чуканова, Е. А., Леонтьев, А., & Аксенов, А. (2023). A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene: This article belongs to the Special Issue Synthesis of Bioactive Compounds. Molecules, 28(9), [3657]. https://doi.org/10.3390/molecules28093657

Vancouver

Аксенов Н, Куренков И, Арутюнов Н, Малюга В, Аксенов Д, Момотова Д и пр. A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene: This article belongs to the Special Issue Synthesis of Bioactive Compounds. Molecules. 2023 Апр. 23;28(9). 3657. https://doi.org/10.3390/molecules28093657

Author

Аксенов, Николай ; Куренков, Игорь ; Арутюнов, Николай ; Малюга, Владимир ; Аксенов, Дмитрий ; Момотова, Дарья ; Зацепилина, Анна ; Чуканова, Елизавета Александровна ; Леонтьев, Александр ; Аксенов, Александр. / A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene : This article belongs to the Special Issue Synthesis of Bioactive Compounds. в: Molecules. 2023 ; Том 28, № 9.

BibTeX

@article{956b82e0d5df4d8cabbfc214bd7439ae,
title = "A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene: This article belongs to the Special Issue Synthesis of Bioactive Compounds",
abstract = "A novel, low-cost method for the preparation of not easily accessible free 3-aminoindoles has been developed. This approach is based on a well-established reaction between indoles and nitrostyrene in the presence of phosphorous acid, which results in the formation of 4'-phenyl-4'H-spiro[indole-3,5'-isoxazoles]. The latter could be transformed to corresponding aminated indoles by reaction with hydrazine hydrate in good or excellent yields upon microwave-assisted heating.",
keywords = "C3-amination of indoles, cascade transformations, phenylacetonitrile extrusion",
author = "Николай Аксенов and Игорь Куренков and Николай Арутюнов and Владимир Малюга and Дмитрий Аксенов and Дарья Момотова and Анна Зацепилина and Чуканова, {Елизавета Александровна} and Александр Леонтьев and Александр Аксенов",
year = "2023",
month = apr,
day = "23",
doi = "10.3390/molecules28093657",
language = "English",
volume = "28",
journal = "Molecules",
issn = "1420-3049",
publisher = "MDPI AG",
number = "9",

}

RIS

TY - JOUR

T1 - A Two-Step Synthesis of Unprotected 3-Aminoindoles via Post Functionalization with Nitrostyrene

T2 - This article belongs to the Special Issue Synthesis of Bioactive Compounds

AU - Аксенов, Николай

AU - Куренков, Игорь

AU - Арутюнов, Николай

AU - Малюга, Владимир

AU - Аксенов, Дмитрий

AU - Момотова, Дарья

AU - Зацепилина, Анна

AU - Чуканова, Елизавета Александровна

AU - Леонтьев, Александр

AU - Аксенов, Александр

PY - 2023/4/23

Y1 - 2023/4/23

N2 - A novel, low-cost method for the preparation of not easily accessible free 3-aminoindoles has been developed. This approach is based on a well-established reaction between indoles and nitrostyrene in the presence of phosphorous acid, which results in the formation of 4'-phenyl-4'H-spiro[indole-3,5'-isoxazoles]. The latter could be transformed to corresponding aminated indoles by reaction with hydrazine hydrate in good or excellent yields upon microwave-assisted heating.

AB - A novel, low-cost method for the preparation of not easily accessible free 3-aminoindoles has been developed. This approach is based on a well-established reaction between indoles and nitrostyrene in the presence of phosphorous acid, which results in the formation of 4'-phenyl-4'H-spiro[indole-3,5'-isoxazoles]. The latter could be transformed to corresponding aminated indoles by reaction with hydrazine hydrate in good or excellent yields upon microwave-assisted heating.

KW - C3-amination of indoles

KW - cascade transformations

KW - phenylacetonitrile extrusion

UR - https://www.mendeley.com/catalogue/69066d5f-8ddc-3d9d-bb06-fc95a45457d3/

U2 - 10.3390/molecules28093657

DO - 10.3390/molecules28093657

M3 - Article

C2 - 37175067

VL - 28

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 9

M1 - 3657

ER -

ID: 108527311