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Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки. / Raskin, G. A.; Yanus, G. A.; Kornilov, A. V.; Orlova, R. V.; Petrov, S. V.; Protasova, A. E.; Pozharisski, K. M.; Imyanitov, E. N.

в: Вопросы онкологии, Том 60, № 2, 2014, стр. 47-50.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Raskin, GA, Yanus, GA, Kornilov, AV, Orlova, RV, Petrov, SV, Protasova, AE, Pozharisski, KM & Imyanitov, EN 2014, 'Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки', Вопросы онкологии, Том. 60, № 2, стр. 47-50. https://doi.org/10.37469/0507-3758-2014-60-2-47-50

APA

Raskin, G. A., Yanus, G. A., Kornilov, A. V., Orlova, R. V., Petrov, S. V., Protasova, A. E., Pozharisski, K. M., & Imyanitov, E. N. (2014). Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки. Вопросы онкологии, 60(2), 47-50. https://doi.org/10.37469/0507-3758-2014-60-2-47-50

Vancouver

Raskin GA, Yanus GA, Kornilov AV, Orlova RV, Petrov SV, Protasova AE и пр. Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки. Вопросы онкологии. 2014;60(2):47-50. https://doi.org/10.37469/0507-3758-2014-60-2-47-50

Author

Raskin, G. A. ; Yanus, G. A. ; Kornilov, A. V. ; Orlova, R. V. ; Petrov, S. V. ; Protasova, A. E. ; Pozharisski, K. M. ; Imyanitov, E. N. / Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки. в: Вопросы онкологии. 2014 ; Том 60, № 2. стр. 47-50.

BibTeX

@article{6844a74eb8c849cf868f04963298e50d,
title = "Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки",
abstract = "Adenocarcinoma of the colon in 10-20% is associated with microsatellite instability, which can occur both in sporadic cancers and in hereditary nonpolyposis colon cancer. Our analysis of 195 cases of adenocarcinoma of the colon showed that microsatellite instability (MSI-H) was found only in 1.5% of patients. Subsequent choice of patients with suspected hereditary Lynch syndrome led to the identification of additional 17 patients with microsatellite instability. They passed an analysis of genes of repair system of unpaired nucleotides of DNA. The study showed that immunohistochemical staining of MSH2, MSH6, MLH1, PMS2 could effectively conduct a preliminary screening of the Lynch syndrome but was unable to divide cases of sporadic and hereditary MSI-H colon cancer.",
keywords = "Microsatellite instability, MLH1, MSH2, MSH6, PMS2",
author = "Raskin, {G. A.} and Yanus, {G. A.} and Kornilov, {A. V.} and Orlova, {R. V.} and Petrov, {S. V.} and Protasova, {A. E.} and Pozharisski, {K. M.} and Imyanitov, {E. N.}",
note = "Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",
year = "2014",
doi = "10.37469/0507-3758-2014-60-2-47-50",
language = "русский",
volume = "60",
pages = "47--50",
journal = "Вопросы онкологии",
issn = "0507-3758",
publisher = "Медицина",
number = "2",

}

RIS

TY - JOUR

T1 - Иммуногистохимическое исследование MSH2, PMS2, MLH1, MSH6 в сопоставлении с анализом микросателлитной нестабильности в аденокарциноме толстой кишки

AU - Raskin, G. A.

AU - Yanus, G. A.

AU - Kornilov, A. V.

AU - Orlova, R. V.

AU - Petrov, S. V.

AU - Protasova, A. E.

AU - Pozharisski, K. M.

AU - Imyanitov, E. N.

N1 - Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 2014

Y1 - 2014

N2 - Adenocarcinoma of the colon in 10-20% is associated with microsatellite instability, which can occur both in sporadic cancers and in hereditary nonpolyposis colon cancer. Our analysis of 195 cases of adenocarcinoma of the colon showed that microsatellite instability (MSI-H) was found only in 1.5% of patients. Subsequent choice of patients with suspected hereditary Lynch syndrome led to the identification of additional 17 patients with microsatellite instability. They passed an analysis of genes of repair system of unpaired nucleotides of DNA. The study showed that immunohistochemical staining of MSH2, MSH6, MLH1, PMS2 could effectively conduct a preliminary screening of the Lynch syndrome but was unable to divide cases of sporadic and hereditary MSI-H colon cancer.

AB - Adenocarcinoma of the colon in 10-20% is associated with microsatellite instability, which can occur both in sporadic cancers and in hereditary nonpolyposis colon cancer. Our analysis of 195 cases of adenocarcinoma of the colon showed that microsatellite instability (MSI-H) was found only in 1.5% of patients. Subsequent choice of patients with suspected hereditary Lynch syndrome led to the identification of additional 17 patients with microsatellite instability. They passed an analysis of genes of repair system of unpaired nucleotides of DNA. The study showed that immunohistochemical staining of MSH2, MSH6, MLH1, PMS2 could effectively conduct a preliminary screening of the Lynch syndrome but was unable to divide cases of sporadic and hereditary MSI-H colon cancer.

KW - Microsatellite instability

KW - MLH1

KW - MSH2

KW - MSH6

KW - PMS2

UR - http://www.scopus.com/inward/record.url?scp=84902837353&partnerID=8YFLogxK

U2 - 10.37469/0507-3758-2014-60-2-47-50

DO - 10.37469/0507-3758-2014-60-2-47-50

M3 - статья

C2 - 24919261

AN - SCOPUS:84902837353

VL - 60

SP - 47

EP - 50

JO - Вопросы онкологии

JF - Вопросы онкологии

SN - 0507-3758

IS - 2

ER -

ID: 34886744