Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Анализ факторов риска и структуры перинатальных потерь у беременных с сахарным диабетом. / Капустин, Роман Викторович; Коптеева, Екатерина Вадимовна; Алексеенкова, Елена Николаевна; Цыбук, Елизавета Михайловна; Аржанова, Ольга Николаевна.
в: ДОКТОР.РУ, Том 20, № 6, 2021, стр. 46-52.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Анализ факторов риска и структуры перинатальных потерь у беременных с сахарным диабетом
AU - Капустин, Роман Викторович
AU - Коптеева, Екатерина Вадимовна
AU - Алексеенкова, Елена Николаевна
AU - Цыбук, Елизавета Михайловна
AU - Аржанова, Ольга Николаевна
PY - 2021
Y1 - 2021
N2 - Study Objective: To analyse risk factors and perinatal mortality structure in patients with various types of diabetes mellitus (DM) over the last 30 years in specialised settings. Study Design: retrospective single-site cohort study. Materials and Methods. We have studied 42 medical records containing cases of perinatal death of foetus or newborn in 1988–2018 in patients with DM1 (n = 20), DM2 (n = 10), gestational DM (n = 12). Study Results. The most common complication in pregnancy was preeclampsia combined with chronic placental insufficiency (47.6%). The most common risk factors of perinatal death were inadequate glycemic control in 1st trimester (69.0%), absence of preconception preparations (66.7%), preconception overweight and obesity (42.8%), and chronic arterial hypertension (28.6%). There were 38.1% antenatal deaths, 16.7% intranatal deaths, and 45.2% cases of postnatal mortality. The major causes of perinatal foetal mortality in 26.2% cases were placental disorders, 16.7% were associated with foetus growth retardation, diabetic fetopathy and respiratory distress syndrome. Conclusion. DM during pregnancy was associated with a higher risk of perinatal death. Timely preconception preparation, BMI normalization and a consolidated approach to term and mode of delivery can reduce the risk of perinatal mortality in women with various types of DM. Keywords: diabetes mellitus, gestational diabetes mellitus, perinatal mortality, stillbirth, obesity, preeclampsia
AB - Study Objective: To analyse risk factors and perinatal mortality structure in patients with various types of diabetes mellitus (DM) over the last 30 years in specialised settings. Study Design: retrospective single-site cohort study. Materials and Methods. We have studied 42 medical records containing cases of perinatal death of foetus or newborn in 1988–2018 in patients with DM1 (n = 20), DM2 (n = 10), gestational DM (n = 12). Study Results. The most common complication in pregnancy was preeclampsia combined with chronic placental insufficiency (47.6%). The most common risk factors of perinatal death were inadequate glycemic control in 1st trimester (69.0%), absence of preconception preparations (66.7%), preconception overweight and obesity (42.8%), and chronic arterial hypertension (28.6%). There were 38.1% antenatal deaths, 16.7% intranatal deaths, and 45.2% cases of postnatal mortality. The major causes of perinatal foetal mortality in 26.2% cases were placental disorders, 16.7% were associated with foetus growth retardation, diabetic fetopathy and respiratory distress syndrome. Conclusion. DM during pregnancy was associated with a higher risk of perinatal death. Timely preconception preparation, BMI normalization and a consolidated approach to term and mode of delivery can reduce the risk of perinatal mortality in women with various types of DM. Keywords: diabetes mellitus, gestational diabetes mellitus, perinatal mortality, stillbirth, obesity, preeclampsia
KW - САХАРНЫЙ ДИАБЕТ, ГЕСТАЦИОННЫЙ САХАРНЫЙ ДИАБЕТ, ПЕРИНАТАЛЬНАЯ СМЕРТНОСТЬ, МЕРТВОРОЖДЕНИЕ, ОЖИРЕНИЕ, ПРЕЭКЛАМПСИЯ
UR - https://www.mendeley.com/catalogue/9d771752-9919-3629-b4e6-21ea4e31e11e/
U2 - 10.31550/1727-2378-2021-20-6-46-52
DO - 10.31550/1727-2378-2021-20-6-46-52
M3 - статья
VL - 20
SP - 46
EP - 52
JO - ДОКТОР.РУ
JF - ДОКТОР.РУ
SN - 1727-2378
IS - 6
ER -
ID: 85149787