Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH2 : A novel entry into the 1,2,4-triazine core. / Lukin, Alexey; Vedekhina, Tatiana; Tovpeko, Dmitry; Zhurilo, Nikolay; Krasavin, Mikhail.
In: RSC Advances, Vol. 6, No. 63, 2016, p. 57956-57959.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Zn-catalyzed hydrohydrazination of propargylamides with BocNHNH2
T2 - A novel entry into the 1,2,4-triazine core
AU - Lukin, Alexey
AU - Vedekhina, Tatiana
AU - Tovpeko, Dmitry
AU - Zhurilo, Nikolay
AU - Krasavin, Mikhail
N1 - Publisher Copyright: This journal is © The Royal Society of Chemistry 2016. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.
PY - 2016
Y1 - 2016
N2 - Hydrohydrazination of a variety of propargylamides with BocNHNH2 under Zn(OTf)2 catalysis, unexpectedly, gave dihydro-1,2,4-triazines with a loss of the protecting group. The initial products can be efficiently aromatized in situ with K3[Fe(CN)6]. This provides a new entry into the medicinally important 1,2,4-triazine core.
AB - Hydrohydrazination of a variety of propargylamides with BocNHNH2 under Zn(OTf)2 catalysis, unexpectedly, gave dihydro-1,2,4-triazines with a loss of the protecting group. The initial products can be efficiently aromatized in situ with K3[Fe(CN)6]. This provides a new entry into the medicinally important 1,2,4-triazine core.
UR - http://www.scopus.com/inward/record.url?scp=84976522938&partnerID=8YFLogxK
U2 - 10.1039/c6ra12664b
DO - 10.1039/c6ra12664b
M3 - Article
AN - SCOPUS:84976522938
VL - 6
SP - 57956
EP - 57959
JO - RSC Advances
JF - RSC Advances
SN - 2046-2069
IS - 63
ER -
ID: 9433911