Based on data on the annual incidence of malaria in Senegal in the period from 2000 to 2021, the
article demonstrates the possibilities of predicting the annual dynamics of the epidemic using the SIR model and the CIR model. A modified SIR model with constant coefficients is constructed, and a description of the CIR balance model with stochastic parameters is given. The question of the accuracy of forecasting the annual statistical indicators of the epidemic when using these models is investigated. As numerical experiments show, the average error in predicting the annual number of sick people compared to actual statistical
data when using the SIR model is quite large, while the CIR model generates more accurate forecasts when compared.