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The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages. / Миленина, Лидия Сергеевна; Крутецкая, Зоя Иринарховна; Антонов, Виктор ; Крутецкая, Нина Иринарховна.

In: Biophysics, Vol. 66, No. 1, 01.2021, p. 77–83.

Research output: Contribution to journal › Article › peer-review

Harvard

Миленина, ЛС, Крутецкая, ЗИ, Антонов, В & Крутецкая, НИ 2021, 'The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages', Biophysics, vol. 66, no. 1, pp. 77–83. https://doi.org/10.1134/s0006350921010115

APA

Миленина, Л. С., Крутецкая, З. И., Антонов, В., & Крутецкая, Н. И. (2021). The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages. Biophysics, 66(1), 77–83. https://doi.org/10.1134/s0006350921010115

Vancouver

Миленина ЛС, Крутецкая ЗИ, Антонов В, Крутецкая НИ. The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages. Biophysics. 2021 Jan;66(1):77–83. https://doi.org/10.1134/s0006350921010115

Author

Миленина, Лидия Сергеевна ; Крутецкая, Зоя Иринарховна ; Антонов, Виктор ; Крутецкая, Нина Иринарховна. / The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages. In: Biophysics. 2021 ; Vol. 66, No. 1. pp. 77–83.

BibTeX

@article{8be32c8070714416ab5a419282029372,
title = "The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages",
abstract = "Using Fura-2AM, a fluorescent Ca 2+ indicator, we have shown for the first time that sigma-1 receptor antagonist - neuroleptic chlorpromazine - significantly inhibits the store-dependent Ca 2+ entry induced by immunomodulators glutoxim as well as molixan and endoplasmic reticulum Са 2+-ATPase inhi-bitors thapsigargin and cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages. ",
keywords = "Keywords: sigma-1 receptors, macrophages, store-dependent Ca, store-dependent Ca2+",
author = "Миленина, {Лидия Сергеевна} and Крутецкая, {Зоя Иринарховна} and Виктор Антонов and Крутецкая, {Нина Иринарховна}",
note = "Publisher Copyright: {\textcopyright} 2021, Pleiades Publishing, Inc.",
year = "2021",
month = jan,
doi = "10.1134/s0006350921010115",
language = "English",
volume = "66",
pages = "77–83",
journal = "Biophysics (Russian Federation)",
issn = "0006-3509",
publisher = "Springer Nature",
number = "1",

}

RIS

TY - JOUR

T1 - The sigma-1 receptor ligand chlorpromazine attenuates store-dependent Ca2+ entry in peritoneal macrophages

AU - Миленина, Лидия Сергеевна

AU - Крутецкая, Зоя Иринарховна

AU - Антонов, Виктор

AU - Крутецкая, Нина Иринарховна

N1 - Publisher Copyright: © 2021, Pleiades Publishing, Inc.

PY - 2021/1

Y1 - 2021/1

N2 - Using Fura-2AM, a fluorescent Ca 2+ indicator, we have shown for the first time that sigma-1 receptor antagonist - neuroleptic chlorpromazine - significantly inhibits the store-dependent Ca 2+ entry induced by immunomodulators glutoxim as well as molixan and endoplasmic reticulum Са 2+-ATPase inhi-bitors thapsigargin and cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages.

AB - Using Fura-2AM, a fluorescent Ca 2+ indicator, we have shown for the first time that sigma-1 receptor antagonist - neuroleptic chlorpromazine - significantly inhibits the store-dependent Ca 2+ entry induced by immunomodulators glutoxim as well as molixan and endoplasmic reticulum Са 2+-ATPase inhi-bitors thapsigargin and cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages.

KW - Keywords: sigma-1 receptors

KW - macrophages

KW - store-dependent Ca

KW - store-dependent Ca2+

UR - http://www.scopus.com/inward/record.url?scp=85104991262&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/2113328f-ca18-37fe-bc43-018d41d1a38c/

U2 - 10.1134/s0006350921010115

DO - 10.1134/s0006350921010115

M3 - Article

VL - 66

SP - 77

EP - 83

JO - Biophysics (Russian Federation)

JF - Biophysics (Russian Federation)

SN - 0006-3509

IS - 1

ER -

ID: 76343259