Research output: Contribution to journal › Article › peer-review
Using Fura-2AM, a fluorescent Ca 2+ indicator, we have shown for the first time that sigma-1 receptor antagonist - neuroleptic chlorpromazine - significantly inhibits the store-dependent Ca 2+ entry induced by immunomodulators glutoxim as well as molixan and endoplasmic reticulum Са 2+-ATPase inhi-bitors thapsigargin and cyclopiazonic acid in rat peritoneal macrophages. The results suggest the involvement of sigma-1 receptors in the regulation of store-dependent Ca 2+ entry in macrophages.
| Original language | English |
|---|---|
| Pages (from-to) | 77–83 |
| Number of pages | 7 |
| Journal | Biophysics |
| Volume | 66 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2021 |
ID: 76343259