Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number

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Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number. / Gromov, Dmitry; Bulla, Ingo; Romero-Severson, Ethan O.

In: Journal of Theoretical Biology, Vol. 462, 07.02.2019, p. 381-390.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{bcc2b864056145089372f4ad39af6a56,

title = "Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number",

abstract = "An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R-0, is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of different treatment strategies on the basic reproduction number. All our results are valid for sufficiently small values of the control. However, in many cases it is possible to extend this analysis to larger values of the control as was illustrated by examples. (C) 2018 Elsevier Ltd. All rights reserved.",

keywords = "Disease control, Basic reproduction number, Treatment, Compartmental epidemic model, Next generation matrix, MODEL, COINFECTION, DYNAMICS, HIV, R-0",

author = "Dmitry Gromov and Ingo Bulla and Romero-Severson, {Ethan O.}",

note = "Funding Information: Research presented in this article was supported by the Laboratory Directed Research and Development program of Los Alamos National Laboratory under project number 20180612ECR . Dmitry Gromov acknowledges the travel grant COLLAB 2018 from St. Petersburg State University. Appendix A Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2019",

month = feb,

day = "7",

doi = "10.1016/j.jtbi.2018.11.029",

language = "Английский",

volume = "462",

pages = "381--390",

journal = "Journal of Theoretical Biology",

issn = "0022-5193",

publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number

AU - Gromov, Dmitry

AU - Bulla, Ingo

AU - Romero-Severson, Ethan O.

N1 - Funding Information: Research presented in this article was supported by the Laboratory Directed Research and Development program of Los Alamos National Laboratory under project number 20180612ECR . Dmitry Gromov acknowledges the travel grant COLLAB 2018 from St. Petersburg State University. Appendix A Publisher Copyright: © 2018 Elsevier Ltd

PY - 2019/2/7

Y1 - 2019/2/7

N2 - An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R-0, is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of different treatment strategies on the basic reproduction number. All our results are valid for sufficiently small values of the control. However, in many cases it is possible to extend this analysis to larger values of the control as was illustrated by examples. (C) 2018 Elsevier Ltd. All rights reserved.

AB - An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R-0, is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of different treatment strategies on the basic reproduction number. All our results are valid for sufficiently small values of the control. However, in many cases it is possible to extend this analysis to larger values of the control as was illustrated by examples. (C) 2018 Elsevier Ltd. All rights reserved.

KW - Disease control

KW - Basic reproduction number

KW - Treatment

KW - Compartmental epidemic model

KW - Next generation matrix

KW - MODEL

KW - COINFECTION

KW - DYNAMICS

KW - HIV

KW - R-0

UR - http://www.scopus.com/inward/record.url?scp=85057451279&partnerID=8YFLogxK

UR - http://www.mendeley.com/research/systematic-evaluation-populationlevel-effects-alternative-treatment-strategies-basic-reproduction-nu

U2 - 10.1016/j.jtbi.2018.11.029

DO - 10.1016/j.jtbi.2018.11.029

M3 - статья

VL - 462

SP - 381

EP - 390

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

ER -

ID: 36612455