Research output: Contribution to journal › Article › peer-review
The glutarimide moiety, common in many immuno-modulatory drugs, was decorated with lactam and diamide side chains via two variants of the Ugi reaction, namely, with isocyanide, aldehyde and acid or with isocyanide and oxo acid. The resulting diastereomerically pure compounds were evaluated for their affinity towards the E3 ubiquitin ligase substrate receptor Cereblon.
| Original language | English |
|---|---|
| Pages (from-to) | 747-749 |
| Number of pages | 3 |
| Journal | Mendeleev Communications |
| Volume | 32 |
| Issue number | 6 |
| DOIs | |
| State | Published - 1 Nov 2022 |
ID: 100705686