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Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate. / Gein, V. L.; Odegova, T. F.; Yankin, A. N.; Nosova, N. V.

In: Russian Journal of General Chemistry, Vol. 85, No. 1, 01.01.2015, p. 46-52.

Research output: Contribution to journal › Article › peer-review

Harvard

Gein, VL, Odegova, TF, Yankin, AN & Nosova, NV 2015, 'Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate', Russian Journal of General Chemistry, vol. 85, no. 1, pp. 46-52. https://doi.org/10.1134/S1070363215010089

APA

Gein, V. L., Odegova, T. F., Yankin, A. N., & Nosova, N. V. (2015). Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate. Russian Journal of General Chemistry, 85(1), 46-52. https://doi.org/10.1134/S1070363215010089

Vancouver

Gein VL, Odegova TF, Yankin AN, Nosova NV. Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate. Russian Journal of General Chemistry. 2015 Jan 1;85(1):46-52. https://doi.org/10.1134/S1070363215010089

Author

Gein, V. L. ; Odegova, T. F. ; Yankin, A. N. ; Nosova, N. V. / Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate. In: Russian Journal of General Chemistry. 2015 ; Vol. 85, No. 1. pp. 46-52.

BibTeX

@article{e9eae849fbeb47c88b40a9f90f980625,
title = "Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate",
abstract = "Reaction of N-arylacetoacetamides with aromatic aldehydes in the presence of piperidine in ethanol afforded N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides. The latter reacted with p-toluidine leading to the formation of dehydration products. Reactions of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate and cyanoacetic acid hydrazide gave rise to tetrahydroindazoles. Some of the obtained compounds showed antimicrobial activity.",
keywords = "antimicrobial activity, cyclohexane-1,3-dicarboxamides, hydrazine hydrate, indazoles, p-toluidine",
author = "Gein, {V. L.} and Odegova, {T. F.} and Yankin, {A. N.} and Nosova, {N. V.}",
year = "2015",
month = jan,
day = "1",
doi = "10.1134/S1070363215010089",
language = "English",
volume = "85",
pages = "46--52",
journal = "Russian Journal of General Chemistry",
issn = "1070-3632",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Synthesis of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides and their reactions with p-toluidine and hydrazine hydrate

AU - Gein, V. L.

AU - Odegova, T. F.

AU - Yankin, A. N.

AU - Nosova, N. V.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Reaction of N-arylacetoacetamides with aromatic aldehydes in the presence of piperidine in ethanol afforded N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides. The latter reacted with p-toluidine leading to the formation of dehydration products. Reactions of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate and cyanoacetic acid hydrazide gave rise to tetrahydroindazoles. Some of the obtained compounds showed antimicrobial activity.

AB - Reaction of N-arylacetoacetamides with aromatic aldehydes in the presence of piperidine in ethanol afforded N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides. The latter reacted with p-toluidine leading to the formation of dehydration products. Reactions of N,N′,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate and cyanoacetic acid hydrazide gave rise to tetrahydroindazoles. Some of the obtained compounds showed antimicrobial activity.

KW - antimicrobial activity

KW - cyclohexane-1,3-dicarboxamides

KW - hydrazine hydrate

KW - indazoles

KW - p-toluidine

UR - http://www.scopus.com/inward/record.url?scp=84923359550&partnerID=8YFLogxK

U2 - 10.1134/S1070363215010089

DO - 10.1134/S1070363215010089

M3 - Article

AN - SCOPUS:84923359550

VL - 85

SP - 46

EP - 52

JO - Russian Journal of General Chemistry

JF - Russian Journal of General Chemistry

SN - 1070-3632

IS - 1

ER -

ID: 36326315