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Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics. / Golubeva, O. Yu.; Shamova, O. V.; Orlov, D. S.; Pazina, T. Yu.; Boldina, A. S.; Drozdova, I. A.; Kokryakov, V. N.

In: Glass Physics and Chemistry, Vol. 37, No. 1, 2011, p. 78-84.

Research output: Contribution to journal › Article › peer-review

Harvard

Golubeva, OY, Shamova, OV, Orlov, DS, Pazina, TY, Boldina, AS, Drozdova, IA & Kokryakov, VN 2011, 'Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics', Glass Physics and Chemistry, vol. 37, no. 1, pp. 78-84. https://doi.org/10.1134/S1087659611010056, https://doi.org/10.1134/S1087659611010056

APA

Golubeva, O. Y., Shamova, O. V., Orlov, D. S., Pazina, T. Y., Boldina, A. S., Drozdova, I. A., & Kokryakov, V. N. (2011). Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics. Glass Physics and Chemistry, 37(1), 78-84. https://doi.org/10.1134/S1087659611010056, https://doi.org/10.1134/S1087659611010056

Vancouver

Golubeva OY, Shamova OV, Orlov DS, Pazina TY, Boldina AS, Drozdova IA et al. Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics. Glass Physics and Chemistry. 2011;37(1):78-84. https://doi.org/10.1134/S1087659611010056, https://doi.org/10.1134/S1087659611010056

Author

Golubeva, O. Yu. ; Shamova, O. V. ; Orlov, D. S. ; Pazina, T. Yu. ; Boldina, A. S. ; Drozdova, I. A. ; Kokryakov, V. N. / Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics. In: Glass Physics and Chemistry. 2011 ; Vol. 37, No. 1. pp. 78-84.

BibTeX

@article{9c81d4d5ea184ae1b9c4104e22f0bb11,
title = "Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics",
abstract = "Bioconjugates of silver nanoparticles and antimicrobial peptides of the bactenecin family, which are endogenous antibiotics, have been synthesized. The biological activity of the prepared bioconjugates has been evaluated. It has been established that the conjugates of silver nanoparticles with the peptide G-Bac3.4 exhibit an antimicrobial activity, including the activity with respect to the strain Pseudomonas aeruginosa resistant to traditional antibiotics and the strain Staphylococcus aureus (MRSA ATCC 33591) resistant to methicillin. It has been demonstrated that the complexes of silver nanoparticles with antimicrobial peptides do not possess a pronounced membranolytic effect inherent in peptides. The results obtained have made it possible to draw the conclusion that the properties of the synthesized conjugates differ from those characteristic of constituting peptides and silver nanoparticles.",
keywords = "convergence, bioconjugates, nanoparticles, silver, antimicrobial peptides, antibiotics, PEPTIDE",
author = "Golubeva, {O. Yu.} and Shamova, {O. V.} and Orlov, {D. S.} and Pazina, {T. Yu.} and Boldina, {A. S.} and Drozdova, {I. A.} and Kokryakov, {V. N.}",
year = "2011",
doi = "10.1134/S1087659611010056",
language = "English",
volume = "37",
pages = "78--84",
journal = "Glass Physics and Chemistry",
issn = "1087-6596",
publisher = "МАИК {"}Наука/Интерпериодика{"}",
number = "1",

}

RIS

TY - JOUR

T1 - Synthesis and study of antimicrobial activity of bioconjugates of silver nanoparticles and endogenous antibiotics

AU - Golubeva, O. Yu.

AU - Shamova, O. V.

AU - Orlov, D. S.

AU - Pazina, T. Yu.

AU - Boldina, A. S.

AU - Drozdova, I. A.

AU - Kokryakov, V. N.

PY - 2011

Y1 - 2011

N2 - Bioconjugates of silver nanoparticles and antimicrobial peptides of the bactenecin family, which are endogenous antibiotics, have been synthesized. The biological activity of the prepared bioconjugates has been evaluated. It has been established that the conjugates of silver nanoparticles with the peptide G-Bac3.4 exhibit an antimicrobial activity, including the activity with respect to the strain Pseudomonas aeruginosa resistant to traditional antibiotics and the strain Staphylococcus aureus (MRSA ATCC 33591) resistant to methicillin. It has been demonstrated that the complexes of silver nanoparticles with antimicrobial peptides do not possess a pronounced membranolytic effect inherent in peptides. The results obtained have made it possible to draw the conclusion that the properties of the synthesized conjugates differ from those characteristic of constituting peptides and silver nanoparticles.

AB - Bioconjugates of silver nanoparticles and antimicrobial peptides of the bactenecin family, which are endogenous antibiotics, have been synthesized. The biological activity of the prepared bioconjugates has been evaluated. It has been established that the conjugates of silver nanoparticles with the peptide G-Bac3.4 exhibit an antimicrobial activity, including the activity with respect to the strain Pseudomonas aeruginosa resistant to traditional antibiotics and the strain Staphylococcus aureus (MRSA ATCC 33591) resistant to methicillin. It has been demonstrated that the complexes of silver nanoparticles with antimicrobial peptides do not possess a pronounced membranolytic effect inherent in peptides. The results obtained have made it possible to draw the conclusion that the properties of the synthesized conjugates differ from those characteristic of constituting peptides and silver nanoparticles.

KW - convergence

KW - bioconjugates

KW - nanoparticles

KW - silver

KW - antimicrobial peptides

KW - antibiotics

KW - PEPTIDE

U2 - 10.1134/S1087659611010056

DO - 10.1134/S1087659611010056

M3 - Article

VL - 37

SP - 78

EP - 84

JO - Glass Physics and Chemistry

JF - Glass Physics and Chemistry

SN - 1087-6596

IS - 1

ER -

ID: 5559399