Research output: Contribution to journal › Article › peer-review
Abstract: New tetrazole-containing derivatives of 2,4-diamino-1,3,5-triazine were synthesized. The cytotoxic activity of the obtained compounds against Huh-7 and HeLa tumor cell lines was studied by the MTT test. The most significant antitumor activity was shown by 1,3,5-triazines containing a 5-phenyltetrazol-2-ylacetohydrazide fragment. The resulting compounds showed practically no cytotoxic effect on non-tumor cells of the human embryonic kidney line HEK293.
Original language | English |
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Pages (from-to) | 1621-1628 |
Number of pages | 8 |
Journal | Russian Journal of General Chemistry |
Volume | 92 |
Issue number | 9 |
DOIs | |
State | Published - 1 Sep 2022 |
ID: 100131646