A rapid and convenient polyol method with microwave irradiation was proposed to synthesize ternary chalcogenide nano-crystal, CuCr₂Se₄, in this study. Nano-crystalline CuCr₂Se₄ was formed from the chemical reaction in the mixture of cuprous chloride, chromium acetate, metallic selenium and poly ethylene glycol under microwave irradiation in argon atmosphere. Crystalline phases were identified with X-ray diffraction analysis and crystal size and morphology were examined by transmission electron microscopy. The result from thermal magnetometric analysis indicated that Curie temperature of nano-sized CuCr₂Se₄ was 445 K with a single phase.