• V.L. Gein
  • A.N. Yankin
  • N.V. Nosova
  • E.B. Levandovskaya
  • V.V. Novikova
  • I.P. Rudakova

Novel 4,5,6,7-tetrahydro-2H-indazole derivatives were obtained via the reaction of N1,N3,2-triaryl-6-hydroxy-6-methyl-4-oxocyclohexane-1,3-dicarboxamides with hydrazine hydrate. The reaction of 4-oxocyclo-hexane-1,3-dicarboxamides with phenylhydrazine led to the formation of hydrazones instead of indazoles. The synthesized compounds were tested for antimicrobial, analgesic and anti-inflammatory activities.

Original languageEnglish
Pages (from-to)1169-1176
Number of pages8
JournalRussian Journal of General Chemistry
Volume89
Issue number6
DOIs
StatePublished - 1 Jun 2019

    Scopus subject areas

  • Chemistry(all)

    Research areas

  • anti-inflammatory activity, antimicrobial activity, hydrazine hydrate, hydrazones, indazoles, phenylhydrazine, GREENER APPROACH, DESIGN, INDAZOLE

ID: 45307239