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Study of DNA interaction with cobalt disulfophthalocyanine. / Tikhomirov, R.; Demidov, V.; Kasyanenko, N.

INTERNATIONAL CONFERENCE PHYSICA.SPB. ed. / NS Averkiev; SA Poniaev; GS Sokolovskii. IOP Publishing Ltd., 2018. (Journal of Physics: Conference Series; Vol. 1038).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

Harvard

Tikhomirov, R, Demidov, V & Kasyanenko, N 2018, Study of DNA interaction with cobalt disulfophthalocyanine. in NS Averkiev, SA Poniaev & GS Sokolovskii (eds), INTERNATIONAL CONFERENCE PHYSICA.SPB. Journal of Physics: Conference Series, vol. 1038, IOP Publishing Ltd., International Conference PhysicA.SPb 2017, Санкт-Петербург, Russian Federation, 24/10/17. https://doi.org/10.1088/1742-6596/1038/1/012026, https://doi.org/10.1088/1742-6596/1038/1/012026

APA

Tikhomirov, R., Demidov, V., & Kasyanenko, N. (2018). Study of DNA interaction with cobalt disulfophthalocyanine. In NS. Averkiev, SA. Poniaev, & GS. Sokolovskii (Eds.), INTERNATIONAL CONFERENCE PHYSICA.SPB (Journal of Physics: Conference Series; Vol. 1038). IOP Publishing Ltd.. https://doi.org/10.1088/1742-6596/1038/1/012026, https://doi.org/10.1088/1742-6596/1038/1/012026

Vancouver

Tikhomirov R, Demidov V, Kasyanenko N. Study of DNA interaction with cobalt disulfophthalocyanine. In Averkiev NS, Poniaev SA, Sokolovskii GS, editors, INTERNATIONAL CONFERENCE PHYSICA.SPB. IOP Publishing Ltd. 2018. (Journal of Physics: Conference Series). https://doi.org/10.1088/1742-6596/1038/1/012026, https://doi.org/10.1088/1742-6596/1038/1/012026

Author

Tikhomirov, R. ; Demidov, V. ; Kasyanenko, N. / Study of DNA interaction with cobalt disulfophthalocyanine. INTERNATIONAL CONFERENCE PHYSICA.SPB. editor / NS Averkiev ; SA Poniaev ; GS Sokolovskii. IOP Publishing Ltd., 2018. (Journal of Physics: Conference Series).

BibTeX

@inproceedings{67f4d4495c0d48208d43ba744a6c861e,
title = "Study of DNA interaction with cobalt disulfophthalocyanine",
abstract = "DNA interaction with disulfophthalocyanine of cobalt (CodSPC) was studied by UVVIS spectrophotometry and low gradient viscometry. The thermal denaturation of DNA in complexes with CodSPC was compared with free DNA denaturation. The small increase in melting temperature indicates that the secondary structure of DNA in complexes is stable. As a results of experimental research the external binding of CodSPC to DNA was determined. The only one type of binding is accompanied by stacking of heterocycles at high concentrations of CodSPC. An increase in viscosity of DNA solutions with the growth of CodSPC concentration can be explained by intermolecular DNA contacts via CodSPC.",
keywords = "BINDING, PHTHALOCYANINE",
author = "R. Tikhomirov and V. Demidov and N. Kasyanenko",
note = "Funding Information: Our study show that CodSPC in experimental condition interacts with DNA. Only one type of binding is realized. The binding is accompanied by changes in CodSPC spectrum and by increase in viscosity of DNA solutions. The binding does not cause destabilization of DNA secondary structure. For better understanding of processes of binding further experiments should be carried out. The support of this work was partially provided by Saint-Petersburg State University Research Park Center of Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics. Publisher Copyright: {\textcopyright} Published under licence by IOP Publishing Ltd. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.; International Conference PhysicA.SPb 2017 ; Conference date: 24-10-2017 Through 26-10-2017",
year = "2018",
month = jun,
day = "18",
doi = "10.1088/1742-6596/1038/1/012026",
language = "English",
series = "Journal of Physics: Conference Series",
publisher = "IOP Publishing Ltd.",
editor = "NS Averkiev and SA Poniaev and GS Sokolovskii",
booktitle = "INTERNATIONAL CONFERENCE PHYSICA.SPB",
address = "United Kingdom",
url = "http://physica.spb.ru/archive/physica2017/",

}

RIS

TY - GEN

T1 - Study of DNA interaction with cobalt disulfophthalocyanine

AU - Tikhomirov, R.

AU - Demidov, V.

AU - Kasyanenko, N.

N1 - Funding Information: Our study show that CodSPC in experimental condition interacts with DNA. Only one type of binding is realized. The binding is accompanied by changes in CodSPC spectrum and by increase in viscosity of DNA solutions. The binding does not cause destabilization of DNA secondary structure. For better understanding of processes of binding further experiments should be carried out. The support of this work was partially provided by Saint-Petersburg State University Research Park Center of Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics. Publisher Copyright: © Published under licence by IOP Publishing Ltd. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2018/6/18

Y1 - 2018/6/18

N2 - DNA interaction with disulfophthalocyanine of cobalt (CodSPC) was studied by UVVIS spectrophotometry and low gradient viscometry. The thermal denaturation of DNA in complexes with CodSPC was compared with free DNA denaturation. The small increase in melting temperature indicates that the secondary structure of DNA in complexes is stable. As a results of experimental research the external binding of CodSPC to DNA was determined. The only one type of binding is accompanied by stacking of heterocycles at high concentrations of CodSPC. An increase in viscosity of DNA solutions with the growth of CodSPC concentration can be explained by intermolecular DNA contacts via CodSPC.

AB - DNA interaction with disulfophthalocyanine of cobalt (CodSPC) was studied by UVVIS spectrophotometry and low gradient viscometry. The thermal denaturation of DNA in complexes with CodSPC was compared with free DNA denaturation. The small increase in melting temperature indicates that the secondary structure of DNA in complexes is stable. As a results of experimental research the external binding of CodSPC to DNA was determined. The only one type of binding is accompanied by stacking of heterocycles at high concentrations of CodSPC. An increase in viscosity of DNA solutions with the growth of CodSPC concentration can be explained by intermolecular DNA contacts via CodSPC.

KW - BINDING

KW - PHTHALOCYANINE

UR - http://www.scopus.com/inward/record.url?scp=85049529055&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/1038/1/012026

DO - 10.1088/1742-6596/1038/1/012026

M3 - Conference contribution

T3 - Journal of Physics: Conference Series

BT - INTERNATIONAL CONFERENCE PHYSICA.SPB

A2 - Averkiev, NS

A2 - Poniaev, SA

A2 - Sokolovskii, GS

PB - IOP Publishing Ltd.

T2 - International Conference PhysicA.SPb 2017

Y2 - 24 October 2017 through 26 October 2017

ER -

ID: 73398702