The paper analyses smart city and smart health concepts and their interrelation. The cases on introduction of technological innovations in healthcare in St. Petersburg a are used as the basis of the analysis. The best practices of innovations in healthcare, based on information-communication technologies, are analyzed. The expert opinions of heads of public and private medical organizations of St. Petersburg are used to identify factors of external and internal environment influencing development of smart health concept on the basis of three elements – smart regulators, smart technologies, smart patients and smart medical organizations. The recommendations for regulatory bodies and medical
organizations concerning enhancement of the process of introduction of innovations are formulated.