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Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis. / Ermolenko, Yu; Anshakova, A.; Osipova, N.; Kamentsev, M.; Maksimenko, O.; Balabanyan, V.; Gelperina, S.

In: Journal of Pharmacological and Toxicological Methods, Vol. 85, 01.05.2017, p. 55-60.

Research output: Contribution to journal › Article › peer-review

Harvard

Ermolenko, Y, Anshakova, A, Osipova, N, Kamentsev, M, Maksimenko, O, Balabanyan, V & Gelperina, S 2017, 'Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis', Journal of Pharmacological and Toxicological Methods, vol. 85, pp. 55-60. https://doi.org/10.1016/j.vascn.2017.01.003

APA

Ermolenko, Y., Anshakova, A., Osipova, N., Kamentsev, M., Maksimenko, O., Balabanyan, V., & Gelperina, S. (2017). Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis. Journal of Pharmacological and Toxicological Methods, 85, 55-60. https://doi.org/10.1016/j.vascn.2017.01.003

Vancouver

Ermolenko Y, Anshakova A, Osipova N, Kamentsev M, Maksimenko O, Balabanyan V et al. Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis. Journal of Pharmacological and Toxicological Methods. 2017 May 1;85:55-60. https://doi.org/10.1016/j.vascn.2017.01.003

Author

Ermolenko, Yu ; Anshakova, A. ; Osipova, N. ; Kamentsev, M. ; Maksimenko, O. ; Balabanyan, V. ; Gelperina, S. / Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis. In: Journal of Pharmacological and Toxicological Methods. 2017 ; Vol. 85. pp. 55-60.

BibTeX

@article{338d69abc8294a0b8c3e6f8301d4170a,
title = "Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis",
abstract = "Capillary zone electrophoresis (CZE) was used for determination of rifabutin (RFB), an anti-tuberculosis antibiotic drug, in various pharmaceutical formulations. Apart from that, simultaneous determination of RFB and human serum albumin (HSA) was performed. Electrophoretic behaviour of RFB was examined at various pH levels. CE conditions: a quartz capillary tube (internal diameter 75 mm, effective length 50 cm, total length 60 cm), the capillary temperature was 25 °С, the voltage applied to the capillary tube was + 20 kV, the UV detection wavelength was 214 nm, hydrodynamic injection of the sample was performed at 30 mbar for 5 s, tetraborate buffer solution (0.01 М, рН 9.2). The obtained results are characterized by high efficiency (number of theoretical plates up to 260,000) and sufficient sensitivity (LOQ starting from 0.02 μg/ml for RFB). The obtained data are in good accord with both HPLC results (for RFB) and spectrophotometry (for HSA).",
keywords = "Capillary electrophoresis (CE), Human serum albumin (HSA), Rifabutin (RFB)",
author = "Yu Ermolenko and A. Anshakova and N. Osipova and M. Kamentsev and O. Maksimenko and V. Balabanyan and S. Gelperina",
year = "2017",
month = may,
day = "1",
doi = "10.1016/j.vascn.2017.01.003",
language = "English",
volume = "85",
pages = "55--60",
journal = "Journal of Pharmacological and Toxicological Methods",
issn = "1056-8719",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Simultaneous determination of rifabutin and human serum albumin in pharmaceutical formulations by capillary electrophoresis

AU - Ermolenko, Yu

AU - Anshakova, A.

AU - Osipova, N.

AU - Kamentsev, M.

AU - Maksimenko, O.

AU - Balabanyan, V.

AU - Gelperina, S.

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Capillary zone electrophoresis (CZE) was used for determination of rifabutin (RFB), an anti-tuberculosis antibiotic drug, in various pharmaceutical formulations. Apart from that, simultaneous determination of RFB and human serum albumin (HSA) was performed. Electrophoretic behaviour of RFB was examined at various pH levels. CE conditions: a quartz capillary tube (internal diameter 75 mm, effective length 50 cm, total length 60 cm), the capillary temperature was 25 °С, the voltage applied to the capillary tube was + 20 kV, the UV detection wavelength was 214 nm, hydrodynamic injection of the sample was performed at 30 mbar for 5 s, tetraborate buffer solution (0.01 М, рН 9.2). The obtained results are characterized by high efficiency (number of theoretical plates up to 260,000) and sufficient sensitivity (LOQ starting from 0.02 μg/ml for RFB). The obtained data are in good accord with both HPLC results (for RFB) and spectrophotometry (for HSA).

AB - Capillary zone electrophoresis (CZE) was used for determination of rifabutin (RFB), an anti-tuberculosis antibiotic drug, in various pharmaceutical formulations. Apart from that, simultaneous determination of RFB and human serum albumin (HSA) was performed. Electrophoretic behaviour of RFB was examined at various pH levels. CE conditions: a quartz capillary tube (internal diameter 75 mm, effective length 50 cm, total length 60 cm), the capillary temperature was 25 °С, the voltage applied to the capillary tube was + 20 kV, the UV detection wavelength was 214 nm, hydrodynamic injection of the sample was performed at 30 mbar for 5 s, tetraborate buffer solution (0.01 М, рН 9.2). The obtained results are characterized by high efficiency (number of theoretical plates up to 260,000) and sufficient sensitivity (LOQ starting from 0.02 μg/ml for RFB). The obtained data are in good accord with both HPLC results (for RFB) and spectrophotometry (for HSA).

KW - Capillary electrophoresis (CE)

KW - Human serum albumin (HSA)

KW - Rifabutin (RFB)

UR - http://www.scopus.com/inward/record.url?scp=85012239706&partnerID=8YFLogxK

U2 - 10.1016/j.vascn.2017.01.003

DO - 10.1016/j.vascn.2017.01.003

M3 - Article

AN - SCOPUS:85012239706

VL - 85

SP - 55

EP - 60

JO - Journal of Pharmacological and Toxicological Methods

JF - Journal of Pharmacological and Toxicological Methods

SN - 1056-8719

ER -

ID: 9517410