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Reversions to respiratory competence of omnipotent sup45 suppressor mutants may be caused by secondary sup45 mutations. / Mironova, L. N.; Samsonova, M. G.; Zhouravleva, G. A.; Kulikov, V. N.; Soom, M. J.

In: Current Genetics, Vol. 27, No. 3, 02.1995, p. 195-200.

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Mironova, L. N. ; Samsonova, M. G. ; Zhouravleva, G. A. ; Kulikov, V. N. ; Soom, M. J. / Reversions to respiratory competence of omnipotent sup45 suppressor mutants may be caused by secondary sup45 mutations. In: Current Genetics. 1995 ; Vol. 27, No. 3. pp. 195-200.

BibTeX

@article{a9fc9ad322cf497187710ba2a02d6c3d,
title = "Reversions to respiratory competence of omnipotent sup45 suppressor mutants may be caused by secondary sup45 mutations",
abstract = "The molecular nature of the sup45 respiratory deficient omnipotent suppressor, and of three reversions to respiratory competence which removed the suppressor effect of the initial mutation, was examined. All reversions were caused by secondary sup45 mutations which indicates a direct connection between sup45 {"}respiratory{"} and {"}translational{"} functions. Computer analysis showed the local changes of Sup45 protein characteristics in the suppressor strain and revertants in comparison to the wild-type protein. The distribution of mutant sites in relation to evolutionary conserved, and tentatively functional, regions in the Sup45 protein is discussed.",
keywords = "Omnipotent suppression, Respiratory deficiency, Sup45 protein structure",
author = "Mironova, {L. N.} and Samsonova, {M. G.} and Zhouravleva, {G. A.} and Kulikov, {V. N.} and Soom, {M. J.}",
year = "1995",
month = feb,
doi = "10.1007/BF00326148",
language = "English",
volume = "27",
pages = "195--200",
journal = "Current Genetics",
issn = "0172-8083",
publisher = "Springer Nature",
number = "3",

}

RIS

TY - JOUR

T1 - Reversions to respiratory competence of omnipotent sup45 suppressor mutants may be caused by secondary sup45 mutations

AU - Mironova, L. N.

AU - Samsonova, M. G.

AU - Zhouravleva, G. A.

AU - Kulikov, V. N.

AU - Soom, M. J.

PY - 1995/2

Y1 - 1995/2

N2 - The molecular nature of the sup45 respiratory deficient omnipotent suppressor, and of three reversions to respiratory competence which removed the suppressor effect of the initial mutation, was examined. All reversions were caused by secondary sup45 mutations which indicates a direct connection between sup45 "respiratory" and "translational" functions. Computer analysis showed the local changes of Sup45 protein characteristics in the suppressor strain and revertants in comparison to the wild-type protein. The distribution of mutant sites in relation to evolutionary conserved, and tentatively functional, regions in the Sup45 protein is discussed.

AB - The molecular nature of the sup45 respiratory deficient omnipotent suppressor, and of three reversions to respiratory competence which removed the suppressor effect of the initial mutation, was examined. All reversions were caused by secondary sup45 mutations which indicates a direct connection between sup45 "respiratory" and "translational" functions. Computer analysis showed the local changes of Sup45 protein characteristics in the suppressor strain and revertants in comparison to the wild-type protein. The distribution of mutant sites in relation to evolutionary conserved, and tentatively functional, regions in the Sup45 protein is discussed.

KW - Omnipotent suppression

KW - Respiratory deficiency

KW - Sup45 protein structure

UR - http://www.scopus.com/inward/record.url?scp=0028924877&partnerID=8YFLogxK

U2 - 10.1007/BF00326148

DO - 10.1007/BF00326148

M3 - Article

C2 - 7736601

AN - SCOPUS:0028924877

VL - 27

SP - 195

EP - 200

JO - Current Genetics

JF - Current Genetics

SN - 0172-8083

IS - 3

ER -

ID: 84958624