QUAST : Quality assessment tool for genome assemblies. / Gurevich, Alexey; Saveliev, Vladislav; Vyahhi, Nikolay; Tesler, Glenn.
In: Bioinformatics, Vol. 29, No. 8, 15.04.2013, p. 1072-1075.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - QUAST
T2 - Quality assessment tool for genome assemblies
AU - Gurevich, Alexey
AU - Saveliev, Vladislav
AU - Vyahhi, Nikolay
AU - Tesler, Glenn
N1 - Copyright: Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013/4/15
Y1 - 2013/4/15
N2 - Limitations of genome sequencing techniques have led to dozens of assembly algorithms, none of which is perfect. A number of methods for comparing assemblers have been developed, but none is yet a recognized benchmark. Further, most existing methods for comparing assemblies are only applicable to new assemblies of finished genomes; the problem of evaluating assemblies of previously unsequenced species has not been adequately considered. Here, we present QUAST - a quality assessment tool for evaluating and comparing genome assemblies. This tool improves on leading assembly comparison software with new ideas and quality metrics. QUAST can evaluate assemblies both with a reference genome, as well as without a reference. QUAST produces many reports, summary tables and plots to help scientists in their research and in their publications. In this study, we used QUAST to compare several genome assemblers on three datasets. QUAST tables and plots for all of them are available in the Supplementary Material, and interactive versions of these reports are on the QUAST website.
AB - Limitations of genome sequencing techniques have led to dozens of assembly algorithms, none of which is perfect. A number of methods for comparing assemblers have been developed, but none is yet a recognized benchmark. Further, most existing methods for comparing assemblies are only applicable to new assemblies of finished genomes; the problem of evaluating assemblies of previously unsequenced species has not been adequately considered. Here, we present QUAST - a quality assessment tool for evaluating and comparing genome assemblies. This tool improves on leading assembly comparison software with new ideas and quality metrics. QUAST can evaluate assemblies both with a reference genome, as well as without a reference. QUAST produces many reports, summary tables and plots to help scientists in their research and in their publications. In this study, we used QUAST to compare several genome assemblers on three datasets. QUAST tables and plots for all of them are available in the Supplementary Material, and interactive versions of these reports are on the QUAST website.
UR - http://www.scopus.com/inward/record.url?scp=84876266928&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btt086
DO - 10.1093/bioinformatics/btt086
M3 - Article
C2 - 23422339
VL - 29
SP - 1072
EP - 1075
JO - Bioinformatics
JF - Bioinformatics
SN - 1367-4803
IS - 8
ER -
ID: 5661497