Research output: Contribution to journal › Article › peer-review
Pullulan Graft Copolymers with Poly(2-oxazoline) Side Groups in Aqueous Solutions: Hydrodynamic Study. / Лезова, Александра Андреевна; Лезов, Алексей Андреевич; Перевязко, Игорь Юрьевич; Рогожин, Вячеслав Борисович; Микушева, Нина Георгиевна; Фетин, Петр Александрович; Сеньчукова, Анна Сергеевна; Михайлова, Мария Евгеньевна; Донец, Алексей Валерьевич; Вовк, Михаил Андреевич; Зорин, Иван Михайлович; Цветков, Николай Викторович.
In: Nanobiotechnology Reports, Vol. 20, No. 1, 01.02.2025, p. 39-44.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Pullulan Graft Copolymers with Poly(2-oxazoline) Side Groups in Aqueous Solutions: Hydrodynamic Study
AU - Лезова, Александра Андреевна
AU - Лезов, Алексей Андреевич
AU - Перевязко, Игорь Юрьевич
AU - Рогожин, Вячеслав Борисович
AU - Микушева, Нина Георгиевна
AU - Фетин, Петр Александрович
AU - Сеньчукова, Анна Сергеевна
AU - Михайлова, Мария Евгеньевна
AU - Донец, Алексей Валерьевич
AU - Вовк, Михаил Андреевич
AU - Зорин, Иван Михайлович
AU - Цветков, Николай Викторович
PY - 2025/2/1
Y1 - 2025/2/1
N2 - Grafted copolymers based on natural polysaccharides are interesting from the standpoint of creating targeted drug delivery systems. The properties of graft copolymers of pullulan with side chains of poly(2-methyl-2-oxazoline) and poly(2-ethyl-2-oxazoline) are studied. The conformational and hydrodynamic characteristics of the indicated polymers, such as the coefficient of translational diffusion, characteristic viscosity, molecular weight, equilibrium rigidity, and hydrodynamic diameter of chains, are determined using nuclear magnetic resonance, dynamic light scattering, analytical ultracentrifugation, viscometry, and a number of combined techniques. Increase of the value of equilibrium rigidity of grafted polymers with poly(2-oxazoline) side chains was detected.
AB - Grafted copolymers based on natural polysaccharides are interesting from the standpoint of creating targeted drug delivery systems. The properties of graft copolymers of pullulan with side chains of poly(2-methyl-2-oxazoline) and poly(2-ethyl-2-oxazoline) are studied. The conformational and hydrodynamic characteristics of the indicated polymers, such as the coefficient of translational diffusion, characteristic viscosity, molecular weight, equilibrium rigidity, and hydrodynamic diameter of chains, are determined using nuclear magnetic resonance, dynamic light scattering, analytical ultracentrifugation, viscometry, and a number of combined techniques. Increase of the value of equilibrium rigidity of grafted polymers with poly(2-oxazoline) side chains was detected.
KW - Graft Copolymers
KW - Hydrodynamic Study
KW - polysaccharides
UR - https://www.mendeley.com/catalogue/d1a40114-597f-31b8-8e8f-5848d88d64a4/
U2 - 10.1134/S263516762560018X
DO - 10.1134/S263516762560018X
M3 - Article
VL - 20
SP - 39
EP - 44
JO - Nanobiotechnology Reports
JF - Nanobiotechnology Reports
SN - 2635-1676
IS - 1
ER -
ID: 137601047