Primary progressive aphasia. / Mikhailov, V. A.; Kotsiubinskaya, Yu V.; Safonova, N. Yu; Ananieva, N. I.; Stulov, I. K.
In: Nevrologiya, Neiropsikhiatriya, Psikhosomatika, Vol. 11, No. 1, 2019, p. 4-11.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Primary progressive aphasia
AU - Mikhailov, V. A.
AU - Kotsiubinskaya, Yu V.
AU - Safonova, N. Yu
AU - Ananieva, N. I.
AU - Stulov, I. K.
N1 - Publisher Copyright: © 2019 Ima-Press Publishing House. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Primary progressive aphasia (PPA) is a heterogeneous group of neurodegenerative diseases related to focal degenerations of the brain and mainly manifested by a gradual loss of speech functions. This symptom is characterized by specific speech disorders. The article presents the etiopathogenic features of PPA, systematizes the clinical criteria for its diagnosis, and describes the modern neuroimaging characteristics of different types of PPA. The proposed PPA severity point scale allows clinicians to record the very early manifestations of aphasia. Modified scales, such as the Frontal Behavioral Inventory (FBI-mod) and the Clinical Dementia Rating (CDR), are also important for specifying the type of PPA.
AB - Primary progressive aphasia (PPA) is a heterogeneous group of neurodegenerative diseases related to focal degenerations of the brain and mainly manifested by a gradual loss of speech functions. This symptom is characterized by specific speech disorders. The article presents the etiopathogenic features of PPA, systematizes the clinical criteria for its diagnosis, and describes the modern neuroimaging characteristics of different types of PPA. The proposed PPA severity point scale allows clinicians to record the very early manifestations of aphasia. Modified scales, such as the Frontal Behavioral Inventory (FBI-mod) and the Clinical Dementia Rating (CDR), are also important for specifying the type of PPA.
KW - Beta amyloid
KW - Dementia
KW - Magnetic resonance imaging with morphometry
KW - Primary progressive aphasia
KW - Tau protein
UR - http://www.scopus.com/inward/record.url?scp=85064459546&partnerID=8YFLogxK
U2 - 10.14412/2074-2711-2019-1-4-11
DO - 10.14412/2074-2711-2019-1-4-11
M3 - Article
AN - SCOPUS:85064459546
VL - 11
SP - 4
EP - 11
JO - Неврология, нейропсихиатрия, психосоматика
JF - Неврология, нейропсихиатрия, психосоматика
SN - 2074-2711
IS - 1
ER -
ID: 88215583