• V. A. Mikhailov
  • Yu V. Kotsiubinskaya
  • N. Yu Safonova
  • N. I. Ananieva
  • I. K. Stulov

Primary progressive aphasia (PPA) is a heterogeneous group of neurodegenerative diseases related to focal degenerations of the brain and mainly manifested by a gradual loss of speech functions. This symptom is characterized by specific speech disorders. The article presents the etiopathogenic features of PPA, systematizes the clinical criteria for its diagnosis, and describes the modern neuroimaging characteristics of different types of PPA. The proposed PPA severity point scale allows clinicians to record the very early manifestations of aphasia. Modified scales, such as the Frontal Behavioral Inventory (FBI-mod) and the Clinical Dementia Rating (CDR), are also important for specifying the type of PPA.

Original languageEnglish
Pages (from-to)4-11
Number of pages8
JournalNevrologiya, Neiropsikhiatriya, Psikhosomatika
Volume11
Issue number1
DOIs
StatePublished - 2019

    Scopus subject areas

  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health

    Research areas

  • Beta amyloid, Dementia, Magnetic resonance imaging with morphometry, Primary progressive aphasia, Tau protein

ID: 88215583