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Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis. / Krasavin, Mikhail; Dar'in, Dmitry; Balalaie, Saeed.

In: Tetrahedron Letters, Vol. 86, 153521, 07.12.2021.

Research output: Contribution to journal › Review article › peer-review

Harvard

Krasavin, M, Dar'in, D & Balalaie, S 2021, 'Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis', Tetrahedron Letters, vol. 86, 153521. https://doi.org/10.1016/j.tetlet.2021.153521

APA

Krasavin, M., Dar'in, D., & Balalaie, S. (2021). Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis. Tetrahedron Letters, 86, [153521]. https://doi.org/10.1016/j.tetlet.2021.153521

Vancouver

Krasavin M, Dar'in D, Balalaie S. Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis. Tetrahedron Letters. 2021 Dec 7;86. 153521. https://doi.org/10.1016/j.tetlet.2021.153521

Author

Krasavin, Mikhail ; Dar'in, Dmitry ; Balalaie, Saeed. / Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis. In: Tetrahedron Letters. 2021 ; Vol. 86.

BibTeX

@article{df2136d17bea4acdbbed1758479c420a,
title = "Post-condensational modifications of the Groebke‐Blackburn‐Bienaym{\'e} reaction products for scaffold-oriented synthesis",
abstract = "Scaffold-generating transformations of the Groebke-Blackburn-Bienaym{\'e} (GBB) reaction products are reviewed. The literature cases were grouped according to the reactions employed as the post-condensational event as follows: lactamization, intramolecular arylation, intramolecular Michael addition, cyclizations involving an alkyne moiety and miscellaneous. Although synthetic strategic based on the post-GBB modifications have been exploited to a lesser extent compared to post-Ugi modifications, the interest of researchers to the GBB reaction as the platform for designing new polycyclic scaffolds has been on the rise in the past decade.",
keywords = "Groebke-Blackburn-Bienaym{\'e} reaction, Isocyanide-base multicomponent reactions, Polycyclic scaffolds, Post-condensational modifications, Scaffold-oriented synthesis, DIVERSE, MULTICOMPONENT REACTIONS, Groebke-Blackburn-Bienayme reaction, Contents, HETEROCYCLES, POT SEQUENTIAL SYNTHESIS, 3-COMPONENT, PYRAZINES, ACCESS",
author = "Mikhail Krasavin and Dmitry Dar'in and Saeed Balalaie",
note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = dec,
day = "7",
doi = "10.1016/j.tetlet.2021.153521",
language = "English",
volume = "86",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Post-condensational modifications of the Groebke‐Blackburn‐Bienaymé reaction products for scaffold-oriented synthesis

AU - Krasavin, Mikhail

AU - Dar'in, Dmitry

AU - Balalaie, Saeed

N1 - Publisher Copyright: © 2021 Elsevier Ltd

PY - 2021/12/7

Y1 - 2021/12/7

N2 - Scaffold-generating transformations of the Groebke-Blackburn-Bienaymé (GBB) reaction products are reviewed. The literature cases were grouped according to the reactions employed as the post-condensational event as follows: lactamization, intramolecular arylation, intramolecular Michael addition, cyclizations involving an alkyne moiety and miscellaneous. Although synthetic strategic based on the post-GBB modifications have been exploited to a lesser extent compared to post-Ugi modifications, the interest of researchers to the GBB reaction as the platform for designing new polycyclic scaffolds has been on the rise in the past decade.

AB - Scaffold-generating transformations of the Groebke-Blackburn-Bienaymé (GBB) reaction products are reviewed. The literature cases were grouped according to the reactions employed as the post-condensational event as follows: lactamization, intramolecular arylation, intramolecular Michael addition, cyclizations involving an alkyne moiety and miscellaneous. Although synthetic strategic based on the post-GBB modifications have been exploited to a lesser extent compared to post-Ugi modifications, the interest of researchers to the GBB reaction as the platform for designing new polycyclic scaffolds has been on the rise in the past decade.

KW - Groebke-Blackburn-Bienaymé reaction

KW - Isocyanide-base multicomponent reactions

KW - Polycyclic scaffolds

KW - Post-condensational modifications

KW - Scaffold-oriented synthesis

KW - DIVERSE

KW - MULTICOMPONENT REACTIONS

KW - Groebke-Blackburn-Bienayme reaction

KW - Contents

KW - HETEROCYCLES

KW - POT SEQUENTIAL SYNTHESIS

KW - 3-COMPONENT

KW - PYRAZINES

KW - ACCESS

UR - http://www.scopus.com/inward/record.url?scp=85118728618&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/23962e98-49b0-3b63-847e-0f4270cf6f7c/

U2 - 10.1016/j.tetlet.2021.153521

DO - 10.1016/j.tetlet.2021.153521

M3 - Review article

AN - SCOPUS:85118728618

VL - 86

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

M1 - 153521

ER -

ID: 88430825