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Plakophilin-2 gene knockout using CRISPR/Cas9 system. / Khudiakov, A. A.; Kostina, D. A.; Kostareva, A. A.; Malashicheva, A. B.

In: Genes and Cells, Vol. 11, No. 2, 01.01.2016, p. 95-99.

Research output: Contribution to journal › Article › peer-review

Harvard

Khudiakov, AA, Kostina, DA, Kostareva, AA & Malashicheva, AB 2016, 'Plakophilin-2 gene knockout using CRISPR/Cas9 system', Genes and Cells, vol. 11, no. 2, pp. 95-99.

APA

Khudiakov, A. A., Kostina, D. A., Kostareva, A. A., & Malashicheva, A. B. (2016). Plakophilin-2 gene knockout using CRISPR/Cas9 system. Genes and Cells, 11(2), 95-99.

Vancouver

Khudiakov AA, Kostina DA, Kostareva AA, Malashicheva AB. Plakophilin-2 gene knockout using CRISPR/Cas9 system. Genes and Cells. 2016 Jan 1;11(2):95-99.

Author

Khudiakov, A. A. ; Kostina, D. A. ; Kostareva, A. A. ; Malashicheva, A. B. / Plakophilin-2 gene knockout using CRISPR/Cas9 system. In: Genes and Cells. 2016 ; Vol. 11, No. 2. pp. 95-99.

BibTeX

@article{06be6142d9864462a3e29d36039a2401,
title = "Plakophilin-2 gene knockout using CRISPR/Cas9 system",
abstract = "CRISPR/Cas9 technology opens up broad prospects for genome manipulations. Generation of gene knockout cell lines is one of the applications of this system. This approach allows to reveal previously unknown gene functions and to reproduce the effect of pathogenic mutations. The purpose of this study was to generate plakofilin-2 gene knockout system and assess its suitability for the study of the functional effect of this knockout.",
keywords = "Cas9, CRISPR, Guide RNA, Knockout, Plakophilin-2, Wnt signaling",
author = "Khudiakov, {A. A.} and Kostina, {D. A.} and Kostareva, {A. A.} and Malashicheva, {A. B.}",
year = "2016",
month = jan,
day = "1",
language = "English",
volume = "11",
pages = "95--99",
journal = "Гены и клетки",
issn = "2313-1829",
publisher = "Институт стволовых клеток человека ",
number = "2",

}

RIS

TY - JOUR

T1 - Plakophilin-2 gene knockout using CRISPR/Cas9 system

AU - Khudiakov, A. A.

AU - Kostina, D. A.

AU - Kostareva, A. A.

AU - Malashicheva, A. B.

PY - 2016/1/1

Y1 - 2016/1/1

N2 - CRISPR/Cas9 technology opens up broad prospects for genome manipulations. Generation of gene knockout cell lines is one of the applications of this system. This approach allows to reveal previously unknown gene functions and to reproduce the effect of pathogenic mutations. The purpose of this study was to generate plakofilin-2 gene knockout system and assess its suitability for the study of the functional effect of this knockout.

AB - CRISPR/Cas9 technology opens up broad prospects for genome manipulations. Generation of gene knockout cell lines is one of the applications of this system. This approach allows to reveal previously unknown gene functions and to reproduce the effect of pathogenic mutations. The purpose of this study was to generate plakofilin-2 gene knockout system and assess its suitability for the study of the functional effect of this knockout.

KW - Cas9

KW - CRISPR

KW - Guide RNA

KW - Knockout

KW - Plakophilin-2

KW - Wnt signaling

UR - http://www.scopus.com/inward/record.url?scp=84995748163&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:84995748163

VL - 11

SP - 95

EP - 99

JO - Гены и клетки

JF - Гены и клетки

SN - 2313-1829

IS - 2

ER -

ID: 35807268